LOCUS SELE 14019 bp DNA PRI 22-AUG-2002 DEFINITION Homo sapiens SELE: selectin E (endothelial adhesion molecule 1) (SELE) gene, complete cds. ACCESSION SELE VERSION tmp KEYWORDS . SOURCE Homo sapiens. ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 14019) AUTHORS Rieder,M.J., Armel,T.Z, Carrington,D.P., Ozuna,M., Kuldanek,S.A, Rajkumar,N., Toth,E.J., Yi,Q. and Nickerson,D.A. TITLE Direct Submission JOURNAL Submitted (22-AUG-2002) Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195, USA COMMENT To cite this work please use: SeattleSNPs. NHLBI HL66682 Program for Genomic Applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu). FEATURES Location/Qualifiers source 1..14019 /organism="Homo sapiens" /db_xref="taxon:9606" repeat_region 1..283 /rpt_family="Alu" /rpt_type=dispersed variation 86 /replace="A" /frequency="0.04" variation 135 /replace="G" /frequency="0.23" variation 194 /replace="C" /frequency="0.22" variation 261 /replace="C" /frequency="0.02" repeat_region 341..436 /rpt_family="L1" /rpt_type=dispersed variation 413 /replace="G" /frequency="0.05" misc_feature 448..574 /note="Region not scanned for variation" repeat_region 535..843 /rpt_family="Alu" /rpt_type=dispersed variation 670 /replace="A" /frequency="0.04" variation 758 /replace="T" /frequency="0.01" variation 1131 /replace="T" /frequency="0.02" variation 1169 /replace="T" /frequency="0.02" variation 1279 /replace="G" /frequency="0.04" variation 1564 /replace="G" /frequency="0.05" mRNA join(1569..1636,1947..2031,2610..2993,3666..3773, 4991..5176,5935..6120,6234..6422,7362..7550,7681..7869, 8083..8259,8802..8909,9680..9701,9807..9879,11099..12968) /gene="SELE" /product="SELE" gene 1569..12968 /gene="SELE" variation 1586 /gene="SELE" /replace="G" /frequency="0.03" variation 1730 /gene="SELE" /replace="A" /frequency="0.01" variation 1774 /gene="SELE" /replace="G" /frequency="0.32" variation 1849 /gene="SELE" /replace="T" /frequency="0.07" variation 1976 /gene="SELE" /replace="T" /frequency="0.06" CDS join(1995..2031,2610..2993,3666..3773,4991..5176, 5935..6120,6234..6422,7362..7550,7681..7869,8083..8259, 8802..8909,9680..9701,9807..9864) /gene="SELE" /codon_start=1 /product="SELE: selectin E (endothelial adhesion molecule 1)" /translation="MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRY THLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEP NNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINN YTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSS METMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGF ELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFT CEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGS SCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGE FTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSG EPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGL SLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL" variation 2043 /gene="SELE" /replace="T" /frequency="0.26" repeat_region 2052..2154 /rpt_family="MER1_type" /rpt_type=dispersed variation 2131 /gene="SELE" /replace="A" /frequency="0.04" variation 2161 /gene="SELE" /replace="A" /frequency="0.05" repeat_region 2174..2348 /rpt_family="MIR" /rpt_type=dispersed variation 2238 /gene="SELE" /replace="-" /frequency="0.96" variation 2239 /gene="SELE" /replace="G" /frequency="0.02" variation 2248 /gene="SELE" /replace="C" /frequency="0.04" variation 2272 /gene="SELE" /replace="A" /frequency="0.01" variation 2408 /gene="SELE" /replace="A" /frequency="0.35" variation 2414 /gene="SELE" /replace="C" /frequency="0.10" variation 2471 /gene="SELE" /replace="C" /frequency="0.30" variation 2633 /gene="SELE" /replace="T" /frequency="0.01" variation 2665 /gene="SELE" /replace="T" /frequency="0.01" variation 2845 /gene="SELE" /replace="G" /frequency="0.06" variation 2848 /gene="SELE" /replace="G" /frequency="0.06" variation 3183..3184 /gene="SELE" /replace="-" /frequency="0.14" variation 3641 /gene="SELE" /replace="C" /frequency="0.05" variation 3689 /gene="SELE" /replace="C" /frequency="0.05" variation 3788 /gene="SELE" /replace="C" /frequency="0.05" repeat_region 3881..4088 /rpt_family="MIR" /rpt_type=dispersed variation 3896 /gene="SELE" /replace="T" /frequency="0.02" variation 3993 /gene="SELE" /replace="A" /frequency="0.06" repeat_region 4174..4322 /rpt_family="MIR" /rpt_type=dispersed variation 4247 /gene="SELE" /replace="A" /frequency="0.18" repeat_region 4327..4537 /rpt_family="MER1_type" /rpt_type=dispersed variation 4464 /gene="SELE" /replace="C" /frequency="0.41" variation 4503..4504 /gene="SELE" /replace="-" /frequency="0.41" variation 4594 /gene="SELE" /replace="G" /frequency="0.04" variation 4611 /gene="SELE" /replace="G" /frequency="0.03" variation 4670 /gene="SELE" /replace="-" /frequency="0.06" variation 4687 /gene="SELE" /replace="A" /frequency="0.06" variation 4920 /gene="SELE" /replace="T" /frequency="0.03" variation 4930 /gene="SELE" /replace="T" /frequency="0.34" variation 4970 /gene="SELE" /replace="C" /frequency="0.03" variation 5668 /gene="SELE" /replace="G" /frequency="0.02" variation 5828 /gene="SELE" /replace="A" /frequency="0.35" variation 5924 /gene="SELE" /replace="A" /frequency="0.21" variation 5960 /gene="SELE" /replace="C" /frequency="0.06" variation 5989 /gene="SELE" /replace="C" /frequency="0.02" variation 6092 /gene="SELE" /replace="C" /frequency="0.01" variation 6102 /gene="SELE" /replace="A" /frequency="0.01" variation 6219 /gene="SELE" /replace="A" /frequency="0.01" variation 6747 /gene="SELE" /replace="G" /frequency="0.23" variation 7003 /gene="SELE" /replace="A" /frequency="0.01" variation 7158 /gene="SELE" /replace="G" /frequency="0.24" variation 7305 /gene="SELE" /replace="A" /frequency="0.24" variation 7532 /gene="SELE" /replace="C" /frequency="0.02" variation 7583 /gene="SELE" /replace="G" /frequency="0.06" variation 7632 /gene="SELE" /replace="A" /frequency="0.02" variation 7673 /gene="SELE" /replace="C" /frequency="0.07" variation 7803 /gene="SELE" /replace="T" /frequency="0.10" variation 7995 /gene="SELE" /replace="A" /frequency="0.07" variation 8517 /gene="SELE" /replace="C" /frequency="0.02" variation 8716 /gene="SELE" /replace="C" /frequency="0.07" variation 8765 /gene="SELE" /replace="T" /frequency="0.02" variation 8804 /gene="SELE" /replace="T" /frequency="0.01" variation 8879 /gene="SELE" /replace="T" /frequency="0.02" variation 8934 /gene="SELE" /replace="T" /frequency="0.01" repeat_region 9119..9183 /rpt_family="Tip100" /rpt_type=dispersed variation 9187 /gene="SELE" /replace="G" /frequency="0.20" variation 9225 /gene="SELE" /replace="T" /frequency="0.01" variation 9258 /gene="SELE" /replace="T" /frequency="0.02" repeat_region 9309..9530 /rpt_family="MER1_type" /rpt_type=dispersed variation 9368 /gene="SELE" /replace="A" /frequency="0.01" variation 9639 /gene="SELE" /replace="T" /frequency="0.04" variation 9831 /gene="SELE" /replace="C" /frequency="0.10" variation 10024..10026 /gene="SELE" /replace="-" /frequency="0.05" variation 10054 /gene="SELE" /replace="G" /frequency="0.27" variation 10087 /gene="SELE" /replace="A" /frequency="0.19" variation 10130 /gene="SELE" /replace="C" /frequency="0.31" repeat_region 10195..10502 /rpt_family="Alu" /rpt_type=dispersed repeat_region 10506..10645 /rpt_family="MIR" /rpt_type=dispersed repeat_region 10693..10976 /rpt_family="L1" /rpt_type=dispersed variation 10728 /gene="SELE" /replace="T" /frequency="0.07" variation 10899 /gene="SELE" /replace="T" /frequency="0.05" variation 11028 /gene="SELE" /replace="T" /frequency="0.01" variation 11029 /gene="SELE" /replace="C" /frequency="0.01" variation 12037 /gene="SELE" /replace="C" /frequency="0.05" variation 12228 /gene="SELE" /replace="G" /frequency="0.20" variation 12618 /gene="SELE" /replace="G" /frequency="0.38" variation 12629 /gene="SELE" /replace="G" /frequency="0.06" variation 13014 /replace="T" /frequency="0.03" variation 13083 /replace="G" /frequency="0.01" repeat_region 13100..13444 /rpt_family="ERVL" /rpt_type=dispersed variation 13249 /replace="G" /frequency="0.04" variation 13252 /replace="C" /frequency="0.36" variation 13311 /replace="C" /frequency="0.23" variation 13432 /replace="-" /frequency="0.20" variation 13434 /replace="T" /frequency="0.03" variation 13435 /replace="G" /frequency="0.01" repeat_region 13483..13520 /rpt_family="ERVL" /rpt_type=dispersed variation 13529 /replace="A" /frequency="0.07" variation 13531 /replace="T" /frequency="0.29" variation 13571 /replace="T" /frequency="0.01" repeat_region 13634..13784 /rpt_family="L2" /rpt_type=dispersed BASE COUNT 4121 a 2655 c 2821 g 4422 t ORIGIN 1 gagatggagt cttgctctgt cgcccaggct ggagtgcaat ggtgtgattt cagctcactg 61 caacctctgc ctcctgggtt caagcgattc tcttgcatca ggctccccag tagctgggat 121 tacaggcatg cgccactaca ccccggctaa tttttgtatt tttagtagag acagggtttc 181 accatattgg ccaggctggt ctggaactcc tgacctcagg tgatccaccc acctcagcct 241 cccaaagtgc tgggattaca ggcatgagcc atcatgcctg gcctagagac aagtttcttt 301 aaactgtatt cttgttacta taaaggtgaa aaaaagggaa attgaaaaaa actttaaaat 361 cctgaaaata ataatgaagg atataaaaat tatcccaaat cctgccatcc agagttagtc 421 actgttaaca ttgtggaaga atttttattc tttgcacatt aacatttcaa aaattttaaa 481 caaaattttg accaattaaa tatatatata tagttttccg ttttattttt tttcttttct 541 tttctttttt tttttttttt tttaagacag agtttcactc gtttcccagg ctggagtgca 601 ctggcgtgat cttggctcac tgcaacctcc acttcccggg ttcaagcgat tctcctgcct 661 cagcctcccg agtagctggg attacaggca tgcgccacca tgcccagcta attttgtatt 721 tttagtagag atggcgtttc tccatgttgg tcaggctggt cttgaactcc cggcctcagg 781 tgatccgcct gcctcggcct cccaaagtgg tgggattaca ggcgtgagcc actgtgcctg 841 gcctcctttt tatttttttc actgaacaaa ccatgaaact ttcccagatg taaatatcta 901 tttcccattt ttcttttttt aaaataaggc attattttaa ccatttgagt gttagatatt 961 atttttagat aatattttaa tttaggcata actgccgtgc aaaatctgaa gattaatatc 1021 taccttgtga gtcattcctc tgtgagacag tgcatgttaa atatgttgaa ttggcaggtg 1081 aaaaaggaag aaaaaatgag tagtgattgg ttatccacag ctatgaatga gaaattgaag 1141 gtagtagact atggatgaca aacctattct tggtttcctt ctgtttctga aattctaatt 1201 actaccacaa ctacatgaga gacactacta acaagcaaag ttttacaact ttttaaagac 1261 atagacttta tgttattata attaaaaatc atgcattttt gtcatattaa taaaattgca 1321 tatacgatat aaaggcatgg acaaaggtga agtagcttca agagacagag tttctgacat 1381 cattgtaatt ttaagcatcg tggatattcc cgggaaagtt tttggatgcc attggggatt 1441 tcctctttac tggatgtgga caatatcctc ctattattca caggaagcaa tccctcctat 1501 aaaagggcct cagccgaagt agtgttcagc tgttcttggc tgacttcaca tcaaaactcc 1561 tatactgacc tgagacagag gcagcagtga tacccacctg agagatcctg tgtttgaaca 1621 actgcttccc aaaacggtaa gtgcagaacg ctttataagg gcagcctcgg gccatgaaac 1681 acagatatgc aaaaggcctt ctaataaaaa ccacatctgt acaagctctt attgtattgt 1741 agctaaaacc tgtcttttct ctttgaccta aataatgaaa gtcttaaaat ttgtttattt 1801 atttgattaa actctgaaat aaagattatt gcactagtgt cctttgccca aaatcttagg 1861 atgctgcctt aaacatcatg gtagaataat gtaactagct acccacgatt tccttcttta 1921 attcattttg tgttttatct ccccaggaaa gtatttcaag cctaaacctt tgggtgaaaa 1981 gaactcttga agtcatgatt gcttcacagt ttctctcagc tctcactttg ggtaagtcag 2041 tgccattaga ccaagatttc tcattctcgc actatagata tttcagactg aaatatcctt 2101 gcttgtctgg ggctgtcctg cacaggatat ctggcagcat ccttgacctc tacctgcaat 2161 gtgttcttcc ctgggcttgg ggtcatttac tttacctctt ggtgtctccc tttccttaag 2221 tgtaaagtgt ggatcataaa tgacctattt cccagatgca ttgtgaggat tcaatagcat 2281 ggttcatgga aagtacctca tacagtgctt cttggtgcat actaagtgct caataaagct 2341 tagttattct gattattatt ctactacaaa atgggtatac tataatgttg tgagtgagtg 2401 tggataaggt acctagtggg tggcagtcac aaaagagata aacaataagt cgctgtttct 2461 tcatacgtac ttcttacttt tgaaaagatg agaaaagtct gggccatgtc acaaacattg 2521 ccaaaaataa gacaataaaa agcacagttg tcagagttaa accacaacag taccaaactc 2581 taccatttct tttctttttc tcccactagt gcttctcatt aaagagagtg gagcctggtc 2641 ttacaacacc tccacggaag ctatgactta tgatgaggcc agtgcttatt gtcagcaaag 2701 gtacacacac ctggttgcaa ttcaaaacaa agaagagatt gagtacctaa actccatatt 2761 gagctattca ccaagttatt actggattgg aatcagaaaa gtcaacaatg tgtgggtctg 2821 ggtaggaacc cagaaacctc tgacagaaga agccaagaac tgggctccag gtgaacccaa 2881 caataggcaa aaagatgagg actgcgtgga gatctacatc aagagagaaa aagatgtggg 2941 catgtggaat gatgagaggt gcagcaagaa gaagcttgcc ctatgctaca caggtaggga 3001 gtttgcggca gcagtgggag gtagtttcag tgtgtgggca tcttggcaaa tttacagcat 3061 gcaaaaactg ctctctattg tggtcatttt atgttccaaa agattctgtt taactgctaa 3121 agtttctctc ttttgctgtt ttgtgtgaat gtgggcaaga atatgtggat atgtatatat 3181 atacacacac acacatatat acacacacac atatatgtgt gtgtgtatat atatatagcc 3241 tacagcattt atatacattt tatatatata catacacaca tatacacaca tatatgtgtg 3301 tatgtatata tataaaatat atataaatac tgtaggcaaa tatgtagttc tttacatata 3361 aaaatgcaca cacacaatac atattttaat tacttgttta tttgtggtag gggaactgtc 3421 ttcagagttt gtgaagaagt aaattttcta cggtaggtgc cagccacagc tatacattag 3481 catcaaggtt taggataggt gggcctgaaa ctcagatttg gaactttgta aaacacttca 3541 gttaaagtct atggcactct gtaggactgc tgatgtctct gttgcacact gttgattcta 3601 aaatcaaagg cactcagtat aagcacagta atagtcctcc tcatcatgct ttgtattttc 3661 cgtagctgcc tgtaccaata catcctgcag tggccacggt gaatgtgtag agaccatcaa 3721 taattacact tgcaagtgtg accctggctt cagtggactc aagtgtgagc aaagtaagtc 3781 tggttcttgc ctctttcttc acttgagatg gtagcaccat ctcacgtcct agctggcatt 3841 agagtcaggt ctgcatgcct tcccttccct ggtgcagatg gtgtcatatg gtgatcgtga 3901 gctgagacta tgaagtcaga ccctgctggg tttgagtcct agattcacca gttatttatt 3961 ttggcacctt gacaagatag tttaactctc tatgtcagtt ttctcattgt aaaatgagga 4021 taataatagt gtgaacttca taggctcatg gttacatggt gcctggcaca caggacacat 4081 tcaataaact gtaattctgt gtccctgcga ggaacatgta ctcacctcat ctaggtggta 4141 acaagacgtt gcagtagaaa tgagtgagtt acagagtcca gggtatcttg gttcatgctc 4201 tggcctctgg ctctgtaatg actagccgtg tagcatggag caagtcgctt gaatgaaatg 4261 aggtctcagt tcctaaattt gtacattaag agagttagat gagcttctct ccaagattcc 4321 ttagcacagc gttgtgcagt agagcttttg tgataatgga aatgttccat agctgtgttt 4381 tccagtgtgt acctatgagc cacatgtggt tattgagtac ttgaaatgtg gctggtgaca 4441 ctgaggaact gaattttaaa tgttatttga tttcaacgaa ttcaagttta aatttgagta 4501 gccacacaga tagtggctac tatagtagac agtgcagcat tagggtttta aaatttgtaa 4561 tgtattctag tacttaaatt tgaaatatag ctttgtgaat ggttctcatc ctggttggaa 4621 gcttactgta gtatttttag cagttgtgag aaaagtaaca agaaatttgt tgtggtacct 4681 aagtttgctg tgtttgttca tataatttga acagttttga ggtaaacaca attacactac 4741 tctccccata tcactcaata tttctttttt atggttgtca tcactgcttt tttgttgttg 4801 ttgttatgga tcagcatttt cttgaataaa agaaaagggg tagaattaca gtcaatttta 4861 caaattccat tagaaatttt ataaattttt aaactaaaaa aaaaaaaaac caaactgtag 4921 ttctagtttc cagtgttctt atctgttaaa ggtgagagat gagcagaact gatttgggtt 4981 tctttttcag ttgtgaactg tacagccctg gaatcccctg agcatggaag cctggtttgc 5041 agtcacccac tgggaaactt cagctacaat tcttcctgct ctatcagctg tgataggggt 5101 tacctgccaa gcagcatgga gaccatgcag tgtatgtcct ctggagaatg gagtgctcct 5161 attccagcct gcaatggtaa atccctctga gaatgcacag aacgttctgt aactcatccc 5221 tcattgcttc tgttttttga ttcaacttac attttcaaaa cttcagggaa agtttttttt 5281 ttgtttttgt ttttaataca atttgttctc tcagccaatg tatattgcca acccagtacc 5341 tgcttgggtt gagagaggtt tttttattct atgcttgaaa tgggtgtttc tgaggctctg 5401 gtgatttgta agggagacca taaaacaata aagctctaga aatctcaatg gatttctcat 5461 cttgtttccc tgtttaactt ttccaagcca tgggactaac ttaagaccat gatagtcaag 5521 cagtcttagt atctcttttt ctctcttaat tttatctttc tgaaccagag gccaaaaaaa 5581 gaaaaatcag ttcttcaggc tctgatgggc taaaataaat gaatagccta cgtatgtcag 5641 tactagtcat aactcctaat ctggaatcta ttttttttaa atttttacct cacgtaaatg 5701 ataacataga ttagagacca ctcagcatag gcaaagtgga aatcagaaaa gatagaatat 5761 ccatgaaaaa gaataaaagc ttttattctg gctgtgcatg tccctaagaa ttgacatagg 5821 actttgggat ctaccctttg aaggcagctt cctcactctg ttaggcaccc agctcaatag 5881 gaagtgaaaa gatcattctt ctgtaaaatt catggtgctc tttcaaatcc tcagtggttg 5941 agtgtgatgc tgtgacaaat ccagccaatg ggttcgtgga atgtttccaa aaccctggaa 6001 gcttcccatg gaacacaacc tgtacatttg actgtgaaga aggatttgaa ctaatgggag 6061 cccagagcct tcagtgtacc tcatctggga attgggacaa cgagaagcca acgtgtaaag 6121 gtagagttgt tccacatgga gacttactgt gaacattctt tctctcaacc catactggaa 6181 atgggcaagc taattctagg ccgtgctaat atcaatgcgt atatttgtta cagctgtgac 6241 atgcagggcc gtccgccagc ctcagaatgg ctctgtgagg tgcagccatt cccctgctgg 6301 agagttcacc ttcaaatcat cctgcaactt cacctgtgag gaaggcttca tgttgcaggg 6361 accagcccag gttgaatgca ccactcaagg gcagtggaca cagcaaatcc cagtttgtga 6421 aggtaagctt gagatccttc gatttatact ttcttaaaga acaaccatct tcaaacttgg 6481 acagtgaaaa aaaaaaccaa tacccacttt aactatagaa atcagatttg atgagcaacc 6541 ctcgtatctt tgagattcat ttaaaagaac taatgtttgg ccagggaaag gatcatatgt 6601 gttaagaatg aattctttgc tgtttttttt taactgtgat gtgctgataa aactttgtag 6661 acattagcat ggaatagaca gaattcttaa tctaaaggaa tcatattaga aaattcggaa 6721 agcagaataa tgagaacatg atttgaatgt aaaactctca tcacacctgt cttctgaaat 6781 ggctcataat tagcagtgat gagactgttt caagcatggt gtcagctaca gagatagtat 6841 tgatgcatat ataagcagta aattttaatt cactttaaag tgagagcaag gatattgaaa 6901 acaagcagtt tttactatca ggcactggcc ttgtcctagc caaagccagc acagaatgat 6961 ttccagtagc aaaacataac acaaaaacca aactgcaaaa cagacaaatt ttataggggt 7021 gctttctttt ctttcttttt ggcaccatct ataaacatcc atgacccata tgttgtcctc 7081 agactgcgtg aaatctttcc ttggaccata atttattttg tgtgttagaa gaacagtgct 7141 caggaactaa tgttctgatt aattagtctt ttaattagtg ccatgatcag tgagggggct 7201 gaaattcaaa gaaaacacag ccatcttccc atttgtccag ggaattataa agaatcttca 7261 gttctccaag tgttgcttga atgaactggg ttcactcaac aaacgccaag tactctctag 7321 ttccactgca atattttctg accatcattt tgatgtctca gctttccagt gcacagcctt 7381 gtccaacccc gagcgaggct acatgaattg tcttcctagt gcttctggca gtttccgtta 7441 tgggtccagc tgtgagttct cctgtgagca gggttttgtg ttgaagggat ccaaaaggct 7501 ccaatgtggc cccacagggg agtgggacaa cgagaagccc acatgtgaag gtacagtctt 7561 tgtttttatt ttattttaag ataaaaagaa ctattgaaga gcttgggaac ttggttacct 7621 tgggaaacgt attgctggag atgcaaacaa acttctaaag tgctctctcg tgtgttccag 7681 ctgtgagatg cgatgctgtc caccagcccc cgaagggttt ggtgaggtgt gctcattccc 7741 ctattggaga attcacctac aagtcctctt gtgccttcag ctgtgaggag ggatttgaat 7801 tacatggatc aactcaactt gagtgcacat ctcagggaca atggacagaa gaggttcctt 7861 cctgccaagg tagaattgag tgcagacttt tttagggtac aggtcaaata cttcataaag 7921 tttctgaacc tagattgccc caaaggggtt tggtcctaat ttcctacatg ctgaaaacta 7981 agtagcgctt acactttaca ttcattgttg acttttaagc aagttttgga agttttccag 8041 tagatttttc tgaaactctg cctgtgtacc taacatttgc agtggtaaaa tgttcaagcc 8101 tggcagttcc gggaaagatc aacatgagct gcagtgggga gcccgtgttt ggcactgtgt 8161 gcaagttcgc ctgtcctgaa ggatggacgc tcaatggctc tgcagctcgg acatgtggag 8221 ccacaggaca ctggtctggc ctgctaccta cctgtgaagg tgatgcattg attgatggtg 8281 gttgtctggt gattaaaaag aaaaaggggg agctatcttg ttacagtaat caactattca 8341 ttatatccaa accagaaagt tcgcccaggt tgacaagttg tgaatattaa gttgtatggg 8401 gatagagaaa aaacagaagt tgcatgttga tggaaagggt agaattctga caactggaaa 8461 aaggagacag agagaggaga ggagaaaggg gaaatggaaa acaagaggga gtgagagcaa 8521 gagagcaagc aagtgcagtg tttattaacc aaggtgtggt gtggtattgt gaacgagctt 8581 ggcaagttag agttctgcct gccaatggtg gaaatagctt caaaggtggc ttggagcaga 8641 tctcaaaggc ctgtaatgcc acatctctgc ttcttgtatt aaactagata gctcttctgc 8701 tcctagtaat gaatgtacag aaaaaaggcc aaagggacag gacggagaga ctttaacatc 8761 aattcttcct catgaccttt cttcgtctct tacttcctta gctcccactg agtccaacat 8821 tcccttggta gctggacttt ctgctgctgg actctccctc ctgacattag caccatttct 8881 cctctggctt cggaaatgct tacggaaagg tgaggaagtt tatgaatgta cttcaaaaat 8941 gtttttgaaa atacatttct ttctcattga taagtcatgg tcttgcttac tgatttaaac 9001 aataattaga atctggataa aatgcagtat aattaagcag aagtattaag aaaagagtta 9061 gtagtacaac tcagtgtggg aagtgtttca ggaaataaaa atgttagtcg tgcctaatat 9121 tgtacaactc cagggggtgc tattcatgtt gaattatatg atgcctcccg gaattgtgca 9181 atggaactgc catgatgagc actctaagga aaatggataa aattcttcct aaggagattt 9241 atttggagta caggcttaaa tttgagagtc tctcataagg aatatggaag cacatctgac 9301 tacactcatg gtttgtttgg cttacatgtt taagagtact taaaacattt ttgagttaag 9361 ttctgacgtt tacaaaatag gaaatctcac atttaaatta agactttgga cttctcatga 9421 aaaattggga gctgaattgg gcaagatgac cccgtagcta tttgctggca ttaggaagct 9481 gctatgccct ttggatggct gtgcactttg cattttaccc tagatgccac agagccatgc 9541 ttgtgctctg attattacag aggccctgaa gcatcgagtt tgcaacactt gatgaattaa 9601 gtcatattgt atctggattt aatatatcct taaaagtcat ttagtctgaa ttaatggttg 9661 tttgtctttt cttttgcagc aaagaaattt gttcctgcca ggtaagttgc attcttatac 9721 aaagcatgcc attgaacatt ccacatattt ttctctcttc atgttggaag acagtgcttt 9781 acctagtgtt ctcatgtatt ccacagcagc tgccaaagcc ttgaatcaga tggaagctac 9841 caaaagcctt cttacatcct ttaagttcaa aagaatcagg taagacttgt aaatcacaaa 9901 tggttatgag agaggtatct tctctacatg ctctgtttct ccttgaaccc tccaaacttg 9961 ccaatatctt agggagggag caggggagaa atcatcacct gggtattgtt ctggaaagtt 10021 gctttatttt ttgtagaagg agaggaaaga aacagatcta gctttattgt gtaatttcat 10081 ttatgataga taataataat gaagatagct gacccttaca ttgcacttat tatattctgg 10141 gaatttttct aagctaggaa ctctgagata ggggctggta ctatatttct tatcttttct 10201 ttttactttt ttttttttta attttgagat ggagtctcat tctgttgcct agactggagt 10261 gcagtggcat gatcttggct cactgcaacc tccacctcct gcgttcaagc aattctcctg 10321 cctcagcctc ctgagtagct gggattacag gtgcctgcca ccacacccag ctaatttttg 10381 tatttttagt agagattttg tattttttcg tcatgttggc caggctgatc ttgaactcct 10441 gatccacccg ccttggcctc tcaaagtgct gggattacag gcgtgagcca ctgggcctgg 10501 cctgttactt tatttcttat cacacagatg aagaaaatga gacagagaag ttaagtaaat 10561 tgtctgaaat ctcaaagcta gtaagtggtg tagccaggat tcaaactctg gcagtctggt 10621 tctaaaattt gtgttcttaa ctactccgac ctgctttgag agaatttgga aaggtcaagt 10681 ccctctgaat actttttaaa aaattaaaat aacttttttt gtgtgtgcgg ttttaagttt 10741 acagaaaaat tgagcagaaa gcacaaagag ttccaacata tctccccacc accccttcaa 10801 ttccccctgt tattaacatc ttatattagt gttacaactg atgggccaat attgatacat 10861 tattattcat taatgtccac aggctacatt agaattcact ctgtgctgtg ttgtatattc 10921 tgtaggtttt gacagaggta taatatgtag acatcatcac tgtcctaact gaatagaatt 10981 cgatgttcct acatggtcta tcctagtgag agtgtctgtg ttagaaggta cattttgttg 11041 tcatgatcag tatgcagaat attaagtgtt ctgatgacat gcatgtttat atttacagaa 11101 acaggtgcat ctggggaact agagggatac actgaagtta acagagacag ataactctcc 11161 tcgggtctct ggcccttctt gcctactatg ccagatgcct ttatggctga aaccgcaaca 11221 cccatcacca cttcaataga tcaaagtcca gcaggcaagg acggccttca actgaaaaga 11281 ctcagtgttc cctttcctac tctcaggatc aagaaagtgt tggctaatga agggaaagga 11341 tattttcttc caagcaaagg tgaagagacc aagactctga aatctcagaa ttccttttct 11401 aactctccct tgctcgctgt aaaatcttgg cacagaaaca caatattttg tggctttctt 11461 tcttttgccc ttcacagtgt ttcgacagct gattacacag ttgctgtcat aagaatgaat 11521 aataattatc cagagtttag aggaaaaaaa tgactaaaaa tattataact taaaaaaatg 11581 acagatgttg aatgcccaca ggcaaatgca tggagggttg ttaatggtgc aaatcctact 11641 gaatgctctg tgcgagggtt actatgcaca atttaatcac tttcatccct atgggattca 11701 gtgcttctta aagagttctt aaggattgtg atatttttac ttgcattgaa tatattataa 11761 tcttccatac ttcttcattc aatacaagtg tggtagggac ttaaaaaact tgtaaatgct 11821 gtcaactatg atatggtaaa agttacttat tctagattac cccctcattg tttattaaca 11881 aattatgtta catctgtttt aaatttattt caaaaaggga aactattgtc cctctagcaa 11941 ggcatgatgt taaccagaat aaagttctga gtgtttttac tacagttgtt ttttgaaaac 12001 atggtagaat tggagagtaa aaactgaatg gaaggtttgt atattgtcag atattttttc 12061 agaaatatgt ggtttccacg atgaaaaact tccatgaggc caaacgtttt gaactaataa 12121 aagcataaat gcaaacacac aaaggtataa ttttatgaat gtctttgttg gaaaagaata 12181 cagaaagatg gatgtgcttt gcattcctac aaagatgttt gtcagatatg atatgtaaac 12241 ataattcttg tatattatgg aagattttaa attcacaata gaaactcacc atgtaaaaga 12301 gtcatctggt agatttttaa cgaatgaaga tgtctaatag ttattcccta tttgttttct 12361 tctgtatgtt agggtgctct ggaagagagg aatgcctgtg tgagcaagca tttatgttta 12421 tttataagca gatttaacaa ttccaaagga atctccagtt ttcagttgat cactggcaat 12481 gaaaaattct cagtcagtaa ttgccaaagc tgctctagcc ttgaggagtg tgagaatcaa 12541 aactctccta cacttccatt aacttagcat gtgttgaaaa aaaagtttca gagaagttct 12601 ggctgaacac tggcaacaac aaagccaaca gtcaaaacag agatgtgata aggatcagaa 12661 cagcagaggt tcttttaaag gggcagaaaa actctgggaa ataagagaga acaactactg 12721 tgatcaggct atgtatggaa tacagtgtta ttttctttga aattgtttaa gtgttgtaaa 12781 tatttatgta aactgcatta gaaattagct gtgtgaaata ccagtgtggt ttgtgtttga 12841 gttttattga gaattttaaa ttataactta aaatatttta taatttttaa agtatatatt 12901 tatttaagct tatgtcagac ctatttgaca taacactata aaggttgaca ataaatgtgc 12961 ttatgtttat ctctgtgtta agtctctttc ttagaaattt tatttagata aaactcactt 13021 tccataaaac gcacccttta aaaatgtatg tgattgtaca gctatcacca ttgtttaact 13081 ccagaagatt tctatcaccc tgataaaaca ttatttctca gtgtgtctgt gagagtattt 13141 ccaaagagat tagtatttaa ttggtagact aagaggattg ccttcaccaa tgtgggtggc 13201 catgatccaa cccattgagg ccctatgtag agcaaaaaga gtgaattcac tgtcttttta 13261 agctgggaca cccatcttct cctgccttcc aacactggca ctcttggttc tagggccttt 13321 ggactttgaa gtattccact ggctttcctg gttctcagct cgtagacagc aggccatggg 13381 acttctcagc ttccataatt gtgtgagaca atttctataa aaaataccac acccccacac 13441 cccaacacac acacgcacac acgcacacac acacacacac accattggtt ctgtttctct 13501 ggagaactcc aactaataca tgtcccttca cgagaactgg ctacttacac taggtctcct 13561 ctttaatgcc ctcataatcc atatgtctct tccttccttt aattgtaata aataattata 13621 gattattact tgcacaattg tttgtttaat gtctgtcttc cccactaaac tctaagttcc 13681 ttaggggtag ggaaaaatta ccttgttcat tgctgtattc ccagaaccta gcacattcct 13741 gatacagagt ggacatccaa caaatattta ttgaatgaat aaatcaatgc atgggtgaat 13801 gaatgcatat tttggctcat aataagaagt agaatcactt ttcacaaatg gaatgagtgg 13861 tctcagaagg ctagacttta aaacctagtt atgtatcaac tgcccccact actgccagtt 13921 tgcaatttaa tatatctatc tctcaaaagt ccagcaatta tttcaatccc catttacaga 13981 aatggggctt gtaggaatca ttgtgagggc taaaggtca //