LOCUS AF405705 13003 bp DNA linear PRI 30-AUG-2001 DEFINITION Homo sapiens matrix metalloproteinase 3 (stromelysin 1, progelatinase) (MMP3) gene, complete cds. ACCESSION AF405705 VERSION AF405705.1 GI:15294139 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 13003) AUTHORS Rieder,M.J., Carrington,D.P., Chung,M.-W., Lee,K.L., Poel,C.L., Yi,Q. and Nickerson,D.A. TITLE Direct Submission JOURNAL Submitted (06-AUG-2001) Molecular Biotechnology, University of Washington, 1705 NE Pacific, Seattle, WA 98195, USA COMMENT To cite this work please use: SeattleSNPs. NHLBI Program for Genomic Applications, UW-FHCRC, Seattle, WA (URL: http://pga.mbt.washington.edu). FEATURES Location/Qualifiers source 1..13003 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" misc_feature 1..540 /note="Region not scanned for variation" repeat_region 580..715 /rpt_family="L2" /rpt_type=dispersed variation 607 /frequency="0.03" /replace="C" variation 621 /frequency="0.01" /replace="G" variation 818 /frequency="0.47" /replace="C" variation 871 /frequency="0.01" /replace="T" variation 1187 /frequency="0.43" /replace="" repeat_region 1246..1363 /rpt_family="AluJb" /rpt_type=dispersed variation 1314 /frequency="0.06" /replace="T" repeat_region 1375..1496 /rpt_family="L3" /rpt_type=dispersed variation 1445 /frequency="0.01" /replace="G" variation 1459 /frequency="0.47" /replace="C" variation 2092 /frequency="0.16" /replace="G" variation 2257 /frequency="0.01" /replace="T" variation 2424 /frequency="0.48" /replace="C" variation 2467 /frequency="0.02" /replace="A" variation 2512 /frequency="0.02" /replace="C" gene 2800..10608 /gene="MMP3" mRNA join(2800..2967,3494..3738,3831..3979,4131..4256, 5817..5981,6158..6302,7167..7300,7700..7859,9009..9112, 10184..10608) /gene="MMP3" /product="matrix metalloproteinase 3 (stromelysin 1, progelatinase)" CDS join(2863..2967,3494..3738,3831..3979,4131..4256, 5817..5981,6158..6302,7167..7300,7700..7859,9009..9112, 10184..10284) /gene="MMP3" /codon_start=1 /product="matrix metalloproteinase 3 (stromelysin 1, progelatinase)" /protein_id="AAK95247.1" /db_xref="GI:15294140" /translation="MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDL KKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRT FPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIM ISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAH EIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVP TEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLRKLEPELHLISSFWP SLPSGVDAAYEVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAI SDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFF TGSSQLEFDPNAKKVTHTLKSNSWLNC" repeat_region 3084..3233 /rpt_family="MIR3" /rpt_type=dispersed variation 3364 /gene="MMP3" /frequency="0.46" /replace="G" variation 3466 /gene="MMP3" /frequency="0.05" /replace="A" variation 3521 /gene="MMP3" /frequency="0.45" /replace="G" variation 3676 /gene="MMP3" /frequency="0.38" /replace="C" misc_feature 3750..3990 /gene="MMP3" /note="Region not scanned for variation" variation 4095 /gene="MMP3" /frequency="0.14" /replace="A" variation 5560 /gene="MMP3" /frequency="0.07" /replace="C" variation 5701 /gene="MMP3" /frequency="0.02" /replace="A" variation 5803 /gene="MMP3" /frequency="0.48" /replace="G" variation 6127 /gene="MMP3" /frequency="0.01" /replace="T" variation 6159 /gene="MMP3" /frequency="0.01" /replace="G" variation 6364 /gene="MMP3" /frequency="0.01" /replace="T" variation 6434 /gene="MMP3" /frequency="0.05" /replace="T" variation 6658 /gene="MMP3" /frequency="0.08" /replace="G" variation 6670 /gene="MMP3" /frequency="0.05" /replace="A" variation 6673 /gene="MMP3" /frequency="0.03" /replace="T" variation 6884 /gene="MMP3" /frequency="0.03" /replace="C" variation 6976 /gene="MMP3" /frequency="0.01" /replace="A" variation 6981 /gene="MMP3" /frequency="0.02" /replace="G" variation 7058 /gene="MMP3" /frequency="0.01" /replace="T" variation 7400 /gene="MMP3" /frequency="0.03" /replace="G" variation 7548 /gene="MMP3" /frequency="0.03" /replace="A" variation 7619 /gene="MMP3" /frequency="0.06" /replace="T" variation 7678..7679 /gene="MMP3" /frequency="0.07" /replace="" variation 7716 /gene="MMP3" /frequency="0.42" /replace="C" repeat_region 8075..8199 /rpt_family="L2" /rpt_type=dispersed variation 8354 /gene="MMP3" /frequency="0.28" /replace="T" variation 8482 /gene="MMP3" /frequency="0.02" /replace="T" variation 8634 /gene="MMP3" /frequency="0.07" /replace="A" variation 8638..8668 /gene="MMP3" /frequency="0.01" /replace="" variation 8669 /gene="MMP3" /frequency="0.01" /replace="T" variation 8730 /gene="MMP3" /frequency="0.01" /replace="G" variation 8803 /gene="MMP3" /frequency="0.02" /replace="A" variation 9227 /gene="MMP3" /frequency="0.42" /replace="C" misc_feature 9400..9600 /gene="MMP3" /note="Region not scanned for variation" variation 9775 /gene="MMP3" /frequency="0.04" /replace="A" variation 9802 /gene="MMP3" /frequency="0.39" /replace="T" variation 9836 /gene="MMP3" /frequency="0.05" /replace="T" repeat_region 9879..10083 /rpt_family="MIR" /rpt_type=dispersed variation 10084 /gene="MMP3" /frequency="0.05" /replace="T" variation 10398 /gene="MMP3" /frequency="0.02" /replace="T" variation 10418 /gene="MMP3" /frequency="0.03" /replace="T" variation 10437 /gene="MMP3" /frequency="0.03" /replace="A" variation 10912 /frequency="0.03" /replace="C" variation 11177 /frequency="0.02" /replace="T" repeat_region 11202..11359 /rpt_family="L2" /rpt_type=dispersed variation 11393 /frequency="0.04" /replace="A" variation 11482 /frequency="0.33" /replace="C" repeat_region 11496..11935 /rpt_family="L2" /rpt_type=dispersed variation 11531 /frequency="0.01" /replace="A" variation 11533 /frequency="0.01" /replace="C" variation 11825 /frequency="0.04" /replace="" variation 11826 /frequency="0.01" /replace="C" variation 11860 /frequency="0.04" /replace="C" variation 12091..12092 /frequency="0.05" /replace="" repeat_region 12220..12310 /rpt_family="L1MC" /rpt_type=dispersed variation 12243 /frequency="0.44" /replace="C" variation 12664 /frequency="0.06" /replace="T" repeat_region 12674..12714 /rpt_family="L1MA4A" /rpt_type=dispersed misc_feature 12886..13003 /note="Region not scanned for variation" repeat_region 12922..13003 /rpt_family="MER6" /rpt_type=dispersed ORIGIN 1 actagccatt atctgaccct tgtatttatt taaccatata acaaatgatt gttctgtgga 61 acagtcattt tgatttcttg ctggaaatgc ccactttttt tccgctagta ttcagttcct 121 ccctctacac ctggagtgtt tgctctcctc ctcccctctc ctcatcttcc tccccctttc 181 tcttctccct ccttctccct ccgttccttc ttacactcag ttgctcttta attttaccta 241 ttccttctca ttactgcatt gatttttaaa acatactcta caaaatgcaa tttgactgtc 301 tcatgcacgg ttagaaaact tctggttcta caagattagt ttgagtgttc tgcagacata 361 tgaatgagga cttcaattat atattagaga gattttagat gatagcttga tcttttcttg 421 tggaaataca acttctaaaa aatttagttt ttagagtatt tagtatatat gacatgtaga 481 atctgcaaat ctagaaatgt ctgcatgatt tttggatttt ttgactttta atttacctgt 541 ttgacatttg ctatgagcct ttcactcata actaatatat tatttagttc tctaagtaat 601 ttttggttac ctactatata tcagatacca tgctaagtac taggaataca gaatcaaatg 661 aggcatggtc cataccctca agtagcttac attagaatga gagagacaga taaaccattt 721 cactacagtt cagtgtggaa aatagagtag cagaggcagg tacaaggtac cattgaacaa 781 tgattaatga ctcttcctgg gacttgggaa acatctttca gggaagtcgt cgaagctgtt 841 ttaaaatata gcaaactttt gtatttagtt caggaacagc atggcccatt ttgccaatca 901 catcttaaca gttggaaaag caaacatatt atctatcagg ctttcctcta aactttaaat 961 atgttttata agttataact ccagagaaaa tttacaaagg ataaacctta atatagaagg 1021 aattagagct gccacagctt ctacactttt aacctctcaa tattttatct gttgggctcc 1081 actgtttctt cctggaattc acatcactgc caccactctg ttctccttgt cctcatatca 1141 atgtggccaa atattttccc tgtatttcaa tcaggacaag acatggtttt ttccccccat 1201 caaaggaatg gagaaccata gaatactagt tttaaaatgt ctttaggcca ggtgccgtga 1261 cccatgtctg taatcctagc actttgagag gttgaggcag gagaatcact tgagcccaga 1321 gctcgaaacc agcctgggca acatagtgaa acctctgtct ctatttttta aataaaattt 1381 gaaaaagtct ttagacataa tctagtctaa aaatgaaggc ttaaatgtga tgtatagccc 1441 cctgccaagt ggctatcaac tgtgtgggca tcttcagtca tagggatctt attgccacag 1501 agaaatccct ttaaacttat tgggtaaaat ctctccaatg tttattaaga aacacacaaa 1561 aaataaagca aagaagaaaa tgcaaaagag ttataaatga gaggaagcaa aatgggcact 1621 tattaaaggt ctaataaatg cacatttgta tccatcattc tactgagttc ttactcccaa 1681 gatgttcttc cctttagcaa acaaataagc aagtcagcaa agaaagaaag aacaaacaaa 1741 atgtggtgat cagggaagca ttgaggagat ggatggtggc aggtggcaag aggactataa 1801 aagttttaca aaatgtcttc ctctgaatat gtttagagtc ttgcattcaa gcatttatta 1861 tacaccaata atgtgagcaa cactttactt gacaaagaaa cagaaaagaa aggaaaggaa 1921 gaaaacagaa gagcatgaag agaaaattta ggatggattc tgttcttcaa cttcaaagca 1981 tctgctaatt tgaatttagg gaggagggga aaaggttgaa agagaataag acatgtgtag 2041 aagacaagga cagagagaat ttcagtccgg taagcaatgt aattcatttc aattctacaa 2101 ctatttatgg agcagctacg tgggcccatc acccattaat aaattggtta cagaattaaa 2161 accaacccaa agggaatata cttccttctt tttcacagac cctctttgtt ctattctgcc 2221 catgaggttt tcctcctcaa gaaccagcaa atccaacgac agtcaatagc aggcattaca 2281 aatcagattc agaaaaataa atcacccctt ctaaatttct tctagatatt atcttttatg 2341 ttttgagtat aattgtatat agtatagact atagctatgt atgtacactt tccacttaca 2401 tcttttattt gcttttataa tgtgtttctt aaaataaaac tgcttttaga agttctgcac 2461 aattctgatt tttaccaagt caacctactt cttctctcaa aaggacaaac ataaattgtc 2521 tagtgaattc cagtcaattt ttccagaaga aaaaaaatgc tccagttttc tcctctacca 2581 agacaggaag cacttcctgg agattaatca ctgtgttgcc ttgcaaaatt gggaaggttg 2641 agagaaatta gtaaagtagg ttgtatcatc ctactttgaa tttggaatgt ttggaaatgg 2701 tcctgctgcc atttggatga aagcaaggat gagtcaagct gcgggtgatc caaacaaaca 2761 ctgtcactct ttaaaagctg cgctcccgag gttggaccta caaggaggca ggcaagacag 2821 caaggcatag agacaacata gagctaagta aagccagtgg aaatgaagag tcttccaatc 2881 ctactgttgc tgtgcgtggc agtttgctca gcctatccat tggatggagc tgcaaggggt 2941 gaggacacca gcatgaacct tgttcaggta attaacacta actgacctgg ccaggtgggg 3001 agcttccaga gtaagctgaa accattctgt gtgtcttaaa acccacatag aatgcttgag 3061 cttactgtgt aggaacagtt caagaataga gagttataga gtgttggaag tggaaaaggt 3121 ctcattatca caccatttgg gcttctcctc ttatgtagga agaaacaaag gccagaaata 3181 ttaggtgttt tcttaagatc acacaacacc atagcagtag cagcactggg gcttaaggca 3241 catgagtaac aagtggagag tggatgaacc atatcttgct ttggaacagc ttcagttttt 3301 ttttttaatg caacgtaatt ttagctaaat atttgtgttg ctagtatcat attataaaat 3361 ttgccattat ttcagcaagc tagagaaata ctccaaatag attaagaagt gagcaactgc 3421 aaaaacttac tataaataga tagctatagt aaaaattgta agagtgacct aaaaactata 3481 cttattctgt tagaaatatc tagaaaacta ctacgacctc aaaaaagatg tgaaacagtt 3541 tgttaggaga aaggacagtg gtcctgttgt taaaaaaatc cgagaaatgc agaagttcct 3601 tggattggag gtgacgggga agctggactc cgacactctg gaggtgatgc gcaagcccag 3661 gtgtggagtt cctgatgttg gtcacttcag aacctttcct ggcatcccga agtggaggaa 3721 aacccacctt acatacaggt aatggttcag aggggttttc acataagatt ggaattttat 3781 aaactatatc ataggagaaa atagcatctg cttcaatttt tctcctacag gattgtgaat 3841 tatacaccag atttgccaaa agatgctgtt gattctgctg ttgagaaagc tctgaaagtc 3901 tgggaagagg tgactccact cacattctcc aggctgtatg aaggagaggc tgatataatg 3961 atctcttttg cagttagagg taaaaaaaaa aaaaaaaaaa aaaaagcaaa acaaaacaaa 4021 acaaaaaaca catgaaatgt atccattcat ctatctggtg ttgttgtact ggaaaaggct 4081 caaaagggat ccttgttaca tatctttcca ataaattttt ttcctactag aacatggaga 4141 cttttaccct tttgatggac ctggaaatgt tttggcccat gcctatgccc ctgggccagg 4201 gattaatgga gatgcccact ttgatgatga tgaacaatgg acaaaggata caacaggtta 4261 gttacacatc tctcagaatg attttggcat taattttttt atatgtagaa atctgttaat 4321 aaccaagaat gctcaagaaa tgagatgttc tggattttcc agtggatcag agatcagcag 4381 aatatatttt tgttttaatt attattgaaa atattttcag atgctttaac agttttccta 4441 tattggtaag cacaatatag gaaatatcat taagtatttc tttaatgact ggatctttgt 4501 gatctagggg taaccattat taagaaaaat ttctcatatc aaaatacaaa cattcaaggg 4561 atagtatatt gcactgaatc tacattaaaa tgtgctctgg atgttactta tgtaatttcc 4621 tccatttact tctttactct tcaaaccaga aataagaatt aaatttcaga aactgagatt 4681 ctcttttttt tttttttctg gctgaggcat tattttagta cttttaggtt aaaagaattt 4741 ttatgggctt gttctgaagg aaaagactaa ctcccaaata caacgttcaa actgtttagg 4801 tagaagaatg tttctcagtt cataactgta tgttttgggg aatgacatcc aaagttttca 4861 aaaaaatcag ctaaaacaat taacactact tctaaaaaaa taggaaaaca attaatacta 4921 tgtctgaggt ttaactggga tttataatga aaatgtaaac ctctgtagga cgtacaaatg 4981 tgagtttagt cctggataga attcttgatt ggttgagtta acgaattctt gtaaagaaac 5041 cttcctgcaa actctcaaat gagattgttc ctagcatcac aagttacaca agtaatacta 5101 gcaaaagtaa ggtagattta cttactatat tgatcataat tacccaatgc ctcccaattt 5161 tagcattatg ggtgttttta aaaatatgaa ggaaaaaatt ttgaataaag ccagtgttta 5221 tgtattctaa atctgttgtg tgacaaatgc tagacatgat tgggcatact gtgttttaaa 5281 ccaattttgc aaatcctatg acatctatca ttattcatgt ttttagtctc aatatgtact 5341 tcatgatgat gaggctgaga cattatcaat taacatgaat atagtttcct ttaactgaga 5401 ctgcaaatgg caaatgtaaa tatattaaaa cagtgtttag ctttgcattg acaaatgaag 5461 gtaaatatct gatatgctaa gcaagtgggt tcattccatt cctgagtaca agaaaaggga 5521 tctggttctt ctggagttaa tatgcttgtg aggctggggg tgggtttggg gccatggggg 5581 gcaagtggat gtaactggga aatcaatctc aaagattgat tacaggtatg agttttaaaa 5641 tacacttagc tttccattaa gtgtgtaatt agtcaattgt tcaattaacc aacaaacaag 5701 gtgtaaaaag ccctgtgtgg ttccaagaag taaaaaccaa tacaatgcac agcagacctg 5761 tgtaatgcac atgtatttaa aaaataagta actattgttc tcaatttctt aaatagggac 5821 caatttattt ctcgttgctg ctcatgaaat tggccactcc ctgggtctct ttcactcagc 5881 caacactgaa gctttgatgt acccactcta tcactcactc acagacctga ctcggttccg 5941 cctgtctcaa gatgatataa atggcattca gtccctctat ggtgagtgac actgggaaaa 6001 tcagccattg tagttttgca atgatggtct tcagaagagc tttcaaatgc tacataaagt 6061 atttatgatt tagttcaaag caccgtgaga atgtttggaa agcatacaaa tgggcatata 6121 ttgaaacgta tcacatttcc cctaatgttc cctttaggac ctccccctga ctcccctgag 6181 acccccctgg tacccacgga acctgtccct ccagaacctg ggacgccagc caactgtgat 6241 cctgctttgt cctttgatgc tgtcagcact ctgaggggag aaatcctgat ctttaaagac 6301 aggtcaggct gaaaaattat attttcctac cattttaatc tacaatgttt agaaaggaaa 6361 acacgcagaa acttgataga gattcttaga catttaaaac aaaaacgttt cttctgagct 6421 tggaatcatt tagatctggt gctgcctttt cccacatttt cctaaaattg tcaggttcat 6481 ttttgaaggc acaggctgat ctggttctta gcttctaatt gctgtttcca aatgtcttaa 6541 gtcacagtta cttttcaaaa ggcatgagta gatctttcga ataataattt tatttttact 6601 tcctttaaaa atgacatcag gatcaacatt acatttaatc aagtaattta cttactgatg 6661 gatcaatatg cacatgacaa acattcaaag agcacaaatg agaagcaaat taaaaatttt 6721 agttcccagt tctccctgta ctcatccaga gtcaagactt tttgtgcatc cttccagaat 6781 ctttctacac acatacaaga atatatttac acagcacata cacgtataca aacacggcct 6841 agcttttgga agagggtata gcacacgcac tgttttgcat acattgcagg taattaaagc 6901 ttatgctggg ctaattcatt tgcacgatag aataattttt ctttcataga agacattact 6961 ctggaaacct atgacgggag actcactaca gtcttctgaa gaaaaaggaa agaaattttc 7021 taatggcaat atacctgatt tctatctgtc atccagccta gaagatgaga gaatggggga 7081 agctgggtga ggcaagacgg tgaggaaaat attctaaagg tgaaagattg tttttcaatt 7141 tacatttctt tttacatata ttttaggcac ttttggcgca aatccctcag gaagcttgaa 7201 cctgaattgc atttgatctc ttcattttgg ccatctcttc cttcaggcgt ggatgccgca 7261 tatgaagtta ctagcaagga cctcgttttc atttttaaag gtaattacta tatcatcatt 7321 tgtttaactt gccaaagtaa accctctcat aagaaattga acaacacttt aattttccct 7381 actacaagtt ctggctaata cagtagtcaa cggtaatgaa gaaataacca gggctgatat 7441 cattgtattt atatttcata gatgataaaa ataaagacaa gaagataaat tacccagagt 7501 tgtaaattct ctcatttgac cttagttcat tcattcagtc tgcaaatttt tgtgaaaagc 7561 ccactgtaag ctggtgacta aatctaaaat ttgggctact actttaccat gaaaatcaaa 7621 gatgctaaag tgtatttcta aagcgaaagg gcttaactgt tataattcaa tatgactctg 7681 aattatttat atttaacagg aaatcaattc tgggctatca gaggaaatga ggtacgagct 7741 ggatacccaa gaggcatcca caccctaggt ttccctccaa ccgtgaggaa aatcgatgca 7801 gccatttctg ataaggaaaa gaacaaaaca tatttctttg tagaggacaa atactggagg 7861 tgagatgcaa gagaaatgac tttgtatgga gcctaattag ggaaattagt ttcttttact 7921 aaggaaatcc cccaccccaa ccttaggcct gcttctctct tagtaggaag gatgggactt 7981 cagacaactg tgggaaagtt cttactttaa aacagcagca ccttaggctc tcctgctttc 8041 agtcccaagt gcagttggct ggtgcttccc ttggtgctgt caccccacct gcctggagcc 8101 ccctcttctc tcctcaacct attcaaatct tgcccatcct tcaagtcctg gctcaagtct 8161 catcacctcc atgcagcttt ccctcgtgga ctttagaccc attgggaaaa tgttctgaga 8221 acccagaccg caatttagcg ttcccttccc attgtctttt agtttggctc actgtctcac 8281 tgtgtgtttg tcactgtctc attgtgtgtt tgttttgtct tcctaacact actatatgat 8341 tttcaagggc tacctctaac ctcacccact tgtcacctct acctgataat gatggctcat 8401 ttaagagatg atgatcaata gcagtccagt ttatggatac aacccaacac tcacagacag 8461 gttgattcct gggtcatttg gccagacttt gagacatcga ggccgaccat ctgatatcca 8521 gccaatgggc taaaaacaca cttactgtgc tttgcttctt atcctaatcc cttttcccag 8581 gaggccacca gagaagattt agatgtgcag gggaggggac agcaggcata tatgggccaa 8641 ttgtggtagg gaattaaaat tgcattttag atgttgattc aattcacttt atatatatgt 8701 tcacactttc atgtctttgt gacagaaaga tgattaaggt tctttctgtc caggcttaag 8761 aaatatgatg acaaacagca tgtgctacat acagcaggat gcggcccctg ttccggatgg 8821 agatatggct ttcagaactc tttacagtac cattaaagtc acatatttct atagtcccaa 8881 atatgcttgg catttatttg cagtatttat aaagtttagt aaaattccac attaaaccta 8941 acatgatcta agatgttcgg taacatggcc tctatgcaat gctgagctgt ttcttttact 9001 tggtacagat ttgatgagaa gagaaattcc atggagccag gctttcccaa gcaaatagct 9061 gaagactttc cagggattga ctcaaagatt gatgctgttt ttgaagaatt tggtaagagg 9121 atacttactg tgttggccat agagcacttg aaacatttta tgatatcaga gggaagagga 9181 gcattgaaac tttttaataa caagtgtttc ttagggccag ttcccttctc aaaattttga 9241 ttcgcctaca tttgtactca ttatagaact acttcacaaa ataacttgtt tggaaccata 9301 aagataatta cacaaatctc gctactttat cttatacatg catataaaat caaagtgctc 9361 cagtgtcact tacatctcga gctaacatgt ggagtcaagc tcgactttca gattaccatg 9421 ttagcataaa aatcccatca agtggtgtgg ccaggtttaa tgttggttag ctggccttct 9481 cctccaccct atcttattgc tgctactaat tcccagggag attttttgtc tgtctttcct 9541 gagttgtcag tcattgccca tgccagtcat ttgcaaatac ttacctttcc atgtgcccaa 9601 agttttaaaa aaaaaaaaga ttttgttttc tactcaaggt aaggaagtgg aggctgatga 9661 tctttattga aaggtaacct gatcaccatg tttgcagagc actaaagggt cccctggtgt 9721 tttgaaatag ttgctgtgct tcctaggctg caatgcaggg aaaagggagg aggatttttg 9781 gggaagaaag aaataggtga tgagagtttc caagcaagtg gagaatttat ctgatcggaa 9841 gcagaataac cctgtaacct ggaatctggc tgtgttttca gacagagctg gcaccgagtg 9901 ctgtctccat tcttccttgc tgagtaacct tgaggaagca tcgaaatctg tctcaacctc 9961 aacttgctca atctgtaaat ggagttagac atacaacctc atagggttgt tgcagaaata 10021 aatgaaaata aattcatgta acaagcttgg catagtccct gacataaagt aaagctctat 10081 aaacactttc tatttttagt tctctatgat tctgagtttt gtatattgtc aaatgtcttt 10141 atttggaaaa atatcttact atttcccttg tctgtatttg cagggttctt ttatttcttt 10201 actggatctt cacagttgga gtttgaccca aatgcaaaga aagtgacaca cactttgaag 10261 agtaacagct ggcttaattg ttgaaagaga tatgtagaag gcacaatatg ggcactttaa 10321 atgaagctaa taattcttca cctaagtctc tgtgaattga aatgttcgtt ttctcctgcc 10381 tgtgctgtga ctcgagtcac actcaaggga acttgagcgt gaatctgtat cttgccggtc 10441 atttttatgt tattacaggg cattcaaatg ggctgctgct tagcttgcac cttgtcacat 10501 agagtgatct ttcccaagag aaggggaagc actcgtgtgc aacagacaag tgactgtatc 10561 tgtgtagact atttgcttat ttaataaaga cgatttgtca gttattttat cttattgttg 10621 tgtttgtttg tttcaagggc aagttgttct cataatttgg gcactttatg ggctgagcat 10681 gctcagcagt agactagagt ctccatggct tggggttcac aatgggttcc agaactgcag 10741 agaatctacc acttgccctc ctcatgagcc ctgcaaacag gatgcttatt tctaccacct 10801 agacatttta tgtgtcctga catacctaag gcaaaaaatc tagaggggtt gtgacattgt 10861 agagcaggct ctaggaaaaa ctgtgaaggg aatcctataa tcatagcaaa ttgccttgtt 10921 tgcacatctc attttacagg gtgaggaaat cagacttgtt tttcatcttt tccttttact 10981 tataaattcc ctcagtgcag gtccctcccc tgacctagca agcaaacttc ctcatatcta 11041 ccctattcac atggtaaaat atactcttgt actcattttg tatctgcctg tgcctggatg 11101 taaatgccca ttggcaaatg acgattctaa cattggttta tcatccataa ctaatgtctc 11161 tagcacaatg cctcgtacat ggtaagagcc gtttttaact tatccattca tctgagagta 11221 atttacaaat catattccat atgccaggca ttatgctagg ttgcaggcat aagaatatga 11281 aaataataga cacaggcccc tgccctcatc gagattataa tccagcgaaa agaacacgtg 11341 tagataacca caaatataaa tacgcaattg taaatttcat aagagttata aagggaaaaa 11401 aataatagga ggatctattt tgaaccagat ggttttagaa gaacttttga gggaatggca 11461 ttgaaggagg ttttgaaagg aggtgtggag actaagaggg gagatgatgg cttggaccac 11521 atgggcacac gggagagtta ggaatgagag tagactctat agatatgaga tagataacag 11581 aacttagtga tggattagat atgcaatttg agagaaaagg aaatgttccg agtaaatcct 11641 aggtagcttg cttgagcata agagctgatg gtgacggcat ttactgagat ggggaaagac 11701 ttggagagaa gaaggtttgt gaaggaaggg caagagttag gatgaatttt ttatgtttgc 11761 ccatttttga aatgtgttgg agaaattcaa gcacccaaga gctaaaggaa tctgaaatgc 11821 aaaagagaca cacacatata tataaaacat atatgtatat ggaaggtttc aacattgaga 11881 ttattcttaa agccagaagt atgggagaga tcatatgggg agagtttaag ataaaactaa 11941 tgaatagcaa catttggtca aaatttacag catttcttta tttttaaaat tacctaattt 12001 tatttatttc taataggtac taccttagcc acaacacaaa atccaaacgt taaaagacat 12061 tatgcaatat aaacaatttt cctcccaccc ctgtttccaa catctaactc cttttctcag 12121 aggtaaccaa gcagatcttt cttgaatcct tccagagcta ttttacgcat accaagcatt 12181 aatataatct ttcaaaataa aaatggtact atgcaaaatt acactgtctt gctctttgat 12241 ttttttcact taatgtatct tggcagctat tccacattag tacatgtaga attgctttat 12301 tcaatttttt tttctttagg tgcacttaat ttaatatcaa gaccacaata caaaaggccc 12361 aaatacaatg aaaaaacaca tttgtccatt aacaccaatg ataatgctct ttcagcacat 12421 gcctgccgaa tggaatgcgg atttaataaa gctcactcct gaaaaaaata acccagtgag 12481 tctcaccaca gccaacatcc ttaagcaatc tggttgtgaa atgaatgttt ataatgcttc 12541 aaacagctta aacctgaagt ttgataccac accttcatgt ttgcacagtt ctcaataaga 12601 ttatctacaa tatttacaac cattcaaagg taaaccattg attaaaacca cattcattta 12661 agactcaata attcccataa atatgtacaa ttattatgta tcaataaaaa agaatcaagt 12721 aatatagagc ctcaaactaa atggttaaat atatgaacga cttatactga caactaatat 12781 ttgattttct gtgactattt aaggttggtt cttagcaaat aatcccttta aaggcaaaat 12841 tcacctcatt tgagttttga cccagcagtt caacaacaat gatgaagttc acagtcttac 12901 tggcaaaacc aatatgttga aaagtcctca tttaacatct ggataagttc ttggaaactc 12961 tgattttaag caaagggatg cataaggaaa ccatttttac cat //