LOCUS AF531102 27864 bp DNA linear PRI 29-JUL-2002 DEFINITION Homo sapiens interleukin 1 receptor, type I (IL1R1) gene, complete cds. ACCESSION AF531102 VERSION AF531102.1 GI:22001412 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 27864) AUTHORS Rieder,M.J., Armel,T.Z., Carrington,D.P., Ozuna,M., Kuldanek,S.A., Rajkumar,N.R., Toth,E.J., Yi,Q. and Nickerson,D.A. TITLE Direct Submission JOURNAL Submitted (18-JUL-2002) Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195, USA COMMENT To cite this work please use: SeattleSNPs. NHLBI HL66682 Program for Genomic Applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu). FEATURES Location/Qualifiers source 1..27864 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" variation 31 /frequency="0.31" /replace="g" variation 48 /frequency="0.03" /replace="t" variation 196 /frequency="0.24" /replace="g" variation 267 /frequency="0.15" /replace="g" variation 342 /frequency="0.04" /replace="c" variation 351 /frequency="0.04" /replace="t" repeat_region 641..710 /rpt_family="L2" /rpt_type=dispersed variation 680 /frequency="0.31" /replace="t" repeat_region 858..1214 /rpt_family="MaLR" /rpt_type=dispersed variation 999 /frequency="0.02" /replace="t" variation 1163 /frequency="0.01" /replace="g" gene 1296..27231 /gene="IL1R1" mRNA join(1296..1371,5073..5139,12129..12363,12470..12659, 13468..13636,15953..16018,19156..19273,20042..20193, 21942..22085,22835..23002,23710..27231) /gene="IL1R1" /product="interleukin 1 receptor, type I" variation 1472 /gene="IL1R1" /frequency="0.03" /replace="c" variation 1632 /gene="IL1R1" /frequency="0.47" /replace="a" variation 1817 /gene="IL1R1" /frequency="0.01" /replace="t" variation 1848 /gene="IL1R1" /frequency="0.01" /replace="a" repeat_region 1958..2116 /rpt_family="L2" /rpt_type=dispersed variation 2176 /gene="IL1R1" /frequency="0.30" /replace="a" variation 2187 /gene="IL1R1" /frequency="0.03" /replace="t" variation 2235 /gene="IL1R1" /frequency="0.30" /replace="t" variation 2300 /gene="IL1R1" /frequency="0.02" /replace="t" repeat_region 2552..2692 /rpt_family="MIR" /rpt_type=dispersed variation 2580 /gene="IL1R1" /frequency="0.01" /replace="t" variation 2689 /gene="IL1R1" /frequency="0.01" /replace="a" variation 2745 /gene="IL1R1" /frequency="0.01" /replace="g" variation 2749 /gene="IL1R1" /frequency="0.19" /replace="g" variation 2759 /gene="IL1R1" /frequency="0.24" /replace="c" variation 3162 /gene="IL1R1" /frequency="0.08" /replace="t" variation 3345 /gene="IL1R1" /frequency="0.02" /replace="a" variation 3563 /gene="IL1R1" /frequency="0.15" /replace="c" repeat_region 3872..4166 /rpt_family="Alu" /rpt_type=dispersed variation 3977 /gene="IL1R1" /frequency="0.49" /replace="c" variation 4442 /gene="IL1R1" /frequency="0.21" /replace="t" variation 4447 /gene="IL1R1" /frequency="0.01" /replace="g" variation 4893 /gene="IL1R1" /frequency="0.11" /replace="t" variation 4909 /gene="IL1R1" /frequency="0.02" /replace="a" variation 4948 /gene="IL1R1" /frequency="0.44" /replace="a" CDS join(5079..5139,12129..12363,12470..12659,13468..13636, 15953..16018,19156..19273,20042..20193,21942..22085, 22835..23002,23710..24116) /gene="IL1R1" /codon_start=1 /product="interleukin 1 receptor, type I" /protein_id="AAM88423.1" /db_xref="GI:22001413" /translation="MKVLLRLICFIALLISSLEADKCKEREEKIILVSSANEIDVRPC PLNPNEHKGTITWYKDDSKTPVSTEQASRIHQHKEKLWFVPAKVEDSGHYYCVVRNSS YCLRIKISAKFVENEPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKNENNELPKLQW YKDCKPLLLDNIHFSGVKDRLIVMNVAEKHRGNYTCHASYTYLGKQYPITRVIEFITL EENKPTRPVIVSPANETMEVDLGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDPVLGE DYYSVENPANKRRSTLITVLNISEIESRFYKHPFTCFAKNTHGIDAAYIQLIYPVTNF QKHMIGICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCYDFLPIKASDGKTYDAYILYP KTVGEGSTSDCDIFVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEVINENVKKSRRL IIILVRETSGFSWLGGSSEEQIAMYNALVQDGIKVVLLELEKIQDYEKMPESIKFIKQ KHGAIRWSGDFTQGPQSAKTRFWKNVRYHMPVQRRSPSSKHQLLSPATKEKLQREAHV PLG" variation 5162 /gene="IL1R1" /frequency="0.03" /replace="c" repeat_region 5286..5447 /rpt_family="MIR" /rpt_type=dispersed repeat_region 5596..6640 /rpt_family="L2" /rpt_type=dispersed variation 5882 /gene="IL1R1" /frequency="0.28" /replace="a" variation 5940 /gene="IL1R1" /frequency="0.02" /replace="c" variation 6038 /gene="IL1R1" /frequency="0.01" /replace="t" variation 6049 /gene="IL1R1" /frequency="0.19" /replace="g" variation 6058 /gene="IL1R1" /frequency="0.15" /replace="t" variation 6147 /gene="IL1R1" /frequency="0.99" /replace="" variation 6220 /gene="IL1R1" /frequency="0.01" /replace="c" variation 6272 /gene="IL1R1" /frequency="0.01" /replace="a" variation 6345 /gene="IL1R1" /frequency="0.04" /replace="a" variation 6529 /gene="IL1R1" /frequency="0.01" /replace="c" variation 6588 /gene="IL1R1" /frequency="0.01" /replace="g" variation 6596 /gene="IL1R1" /frequency="0.04" /replace="g" repeat_region 6645..7409 /rpt_family="L1" /rpt_type=dispersed variation 6991 /gene="IL1R1" /frequency="0.01" /replace="t" variation 7413 /gene="IL1R1" /frequency="0.19" /replace="a" repeat_region 7621..7773 /rpt_family="L1" /rpt_type=dispersed variation 7625 /gene="IL1R1" /frequency="0.04" /replace="a" variation 7750 /gene="IL1R1" /frequency="0.14" /replace="c" repeat_region 7777..8286 /rpt_family="ERVL" /rpt_type=dispersed variation 7821 /gene="IL1R1" /frequency="0.11" /replace="c" repeat_region 8340..9024 /rpt_family="L1" /rpt_type=dispersed variation 8350 /gene="IL1R1" /frequency="0.04" /replace="t" variation 8351..8354 /gene="IL1R1" /frequency="0.03" /replace="" variation 8776 /gene="IL1R1" /frequency="0.01" /replace="g" repeat_region 9025..9356 /rpt_family="Alu" /rpt_type=dispersed variation 9118 /gene="IL1R1" /frequency="0.01" /replace="a" variation 9123 /gene="IL1R1" /frequency="0.01" /replace="t" variation 9259 /gene="IL1R1" /frequency="0.17" /replace="c" variation 9282 /gene="IL1R1" /frequency="0.04" /replace="t" variation 9356 /gene="IL1R1" /frequency="0.47" /replace="t" repeat_region 9357..9456 /rpt_family="L1" /rpt_type=dispersed repeat_region 9457..9557 /rpt_family="L1" /rpt_type=dispersed repeat_region 9558..11832 /rpt_family="L1" /rpt_type=dispersed variation 9612 /gene="IL1R1" /frequency="0.04" /replace="g" variation 9714 /gene="IL1R1" /frequency="0.25" /replace="a" variation 9757 /gene="IL1R1" /frequency="0.05" /replace="t" variation 10087 /gene="IL1R1" /frequency="0.07" /replace="a" variation 10287 /gene="IL1R1" /frequency="0.01" /replace="g" variation 10404 /gene="IL1R1" /frequency="0.04" /replace="a" variation 10515 /gene="IL1R1" /frequency="0.03" /replace="c" variation 10614 /gene="IL1R1" /frequency="0.39" /replace="a" variation 10668 /gene="IL1R1" /frequency="0.01" /replace="c" variation 10839 /gene="IL1R1" /frequency="0.04" /replace="g" variation 10915 /gene="IL1R1" /frequency="0.01" /replace="a" variation 11217 /gene="IL1R1" /frequency="0.01" /replace="a" variation 11257 /gene="IL1R1" /frequency="0.01" /replace="g" variation 11266 /gene="IL1R1" /frequency="0.31" /replace="g" variation 11378 /gene="IL1R1" /frequency="0.01" /replace="a" variation 11548 /gene="IL1R1" /frequency="0.11" /replace="g" variation 11614 /gene="IL1R1" /frequency="0.04" /replace="t" variation 11755 /gene="IL1R1" /frequency="0.05" /replace="g" variation 11781 /gene="IL1R1" /frequency="0.01" /replace="c" repeat_region 11860..12006 /rpt_family="MIR" /rpt_type=dispersed variation 11937 /gene="IL1R1" /frequency="0.05" /replace="t" variation 12061 /gene="IL1R1" /frequency="0.06" /replace="a" variation 12524 /gene="IL1R1" /frequency="0.01" /replace="a" variation 12544 /gene="IL1R1" /frequency="0.08" /replace="g" variation 12751 /gene="IL1R1" /frequency="0.12" /replace="g" variation 12806 /gene="IL1R1" /frequency="0.15" /replace="t" variation 12974 /gene="IL1R1" /frequency="0.26" /replace="t" variation 13061 /gene="IL1R1" /frequency="0.07" /replace="a" variation 13119 /gene="IL1R1" /frequency="0.01" /replace="g" variation 13190 /gene="IL1R1" /frequency="0.02" /replace="c" variation 13328 /gene="IL1R1" /frequency="0.27" /replace="a" variation 13947 /gene="IL1R1" /frequency="0.07" /replace="a" variation 13989 /gene="IL1R1" /frequency="0.01" /replace="a" repeat_region 14055..14163 /rpt_family="MIR" /rpt_type=dispersed variation 14122 /gene="IL1R1" /frequency="0.02" /replace="t" variation 14250 /gene="IL1R1" /frequency="0.36" /replace="t" variation 14334 /gene="IL1R1" /frequency="0.01" /replace="g" repeat_region 14427..14532 /rpt_family="AcHobo" /rpt_type=dispersed repeat_region 14798..15102 /rpt_family="Alu" /rpt_type=dispersed variation 14992 /gene="IL1R1" /frequency="0.02" /replace="t" repeat_region 15236..15350 /rpt_family="L2" /rpt_type=dispersed variation 15728 /gene="IL1R1" /frequency="0.04" /replace="g" variation 15755 /gene="IL1R1" /frequency="0.02" /replace="t" variation 16037 /gene="IL1R1" /frequency="0.01" /replace="c" variation 16053 /gene="IL1R1" /frequency="0.26" /replace="" variation 16150 /gene="IL1R1" /frequency="0.01" /replace="a" variation 16266 /gene="IL1R1" /frequency="0.04" /replace="t" repeat_region 16665..16885 /rpt_family="MER1_type" /rpt_type=dispersed variation 16694 /gene="IL1R1" /frequency="0.03" /replace="t" variation 16749 /gene="IL1R1" /frequency="0.24" /replace="c" variation 16981 /gene="IL1R1" /frequency="0.12" /replace="g" repeat_region 17144..17383 /rpt_family="MER1_type" /rpt_type=dispersed variation 17419 /gene="IL1R1" /frequency="0.06" /replace="a" repeat_region 17591..17809 /rpt_family="L1" /rpt_type=dispersed variation 17704 /gene="IL1R1" /frequency="0.01" /replace="t" variation 17859 /gene="IL1R1" /frequency="0.01" /replace="t" variation 17991 /gene="IL1R1" /frequency="0.01" /replace="t" repeat_region 18134..18417 /rpt_family="Alu" /rpt_type=dispersed variation 18364 /gene="IL1R1" /frequency="0.05" /replace="g" repeat_region 18742..18881 /rpt_family="L1" /rpt_type=dispersed repeat_region 19002..19118 /rpt_family="L1" /rpt_type=dispersed variation 19020 /gene="IL1R1" /frequency="0.28" /replace="t" variation 19304 /gene="IL1R1" /frequency="0.03" /replace="g" variation 19655 /gene="IL1R1" /frequency="0.01" /replace="t" variation 19669 /gene="IL1R1" /frequency="0.27" /replace="a" variation 19734 /gene="IL1R1" /frequency="0.12" /replace="g" variation 20278 /gene="IL1R1" /frequency="0.01" /replace="t" repeat_region 20473..20587 /rpt_family="L2" /rpt_type=dispersed variation 20593 /gene="IL1R1" /frequency="0.05" /replace="c" variation 20752 /gene="IL1R1" /frequency="0.02" /replace="a" repeat_region 20795..21076 /rpt_family="L1" /rpt_type=dispersed variation 20984 /gene="IL1R1" /frequency="0.01" /replace="t" variation 21010 /gene="IL1R1" /frequency="0.04" /replace="g" variation 21077 /gene="IL1R1" /frequency="0.05" /replace="c" variation 21135 /gene="IL1R1" /frequency="0.01" /replace="c" variation 21758 /gene="IL1R1" /frequency="0.08" /replace="c" variation 21920 /gene="IL1R1" /frequency="0.02" /replace="" variation 22164 /gene="IL1R1" /frequency="0.95" /replace="" variation 22276 /gene="IL1R1" /frequency="0.17" /replace="a" variation 22449..22450 /gene="IL1R1" /frequency="0.39" /replace="" repeat_region 23402..23543 /rpt_family="Alu" /rpt_type=dispersed variation 23657 /gene="IL1R1" /frequency="0.29" /replace="g" variation 23738 /gene="IL1R1" /frequency="0.01" /replace="t" variation 23772 /gene="IL1R1" /frequency="0.08" /replace="c" variation 24118 /gene="IL1R1" /frequency="0.01" /replace="g" variation 24143 /gene="IL1R1" /frequency="0.01" /replace="g" variation 24338 /gene="IL1R1" /frequency="0.07" /replace="a" repeat_region 24341..24628 /rpt_family="Alu" /rpt_type=dispersed variation 24430 /gene="IL1R1" /frequency="0.12" /replace="g" variation 24804 /gene="IL1R1" /frequency="0.07" /replace="g" variation 25175 /gene="IL1R1" /frequency="0.01" /replace="t" variation 25179 /gene="IL1R1" /frequency="0.17" /replace="a" variation 25223 /gene="IL1R1" /frequency="0.04" /replace="t" variation 25276 /gene="IL1R1" /frequency="0.04" /replace="g" variation 25438 /gene="IL1R1" /frequency="0.06" /replace="t" variation 25500 /gene="IL1R1" /frequency="0.10" /replace="g" variation 26760 /gene="IL1R1" /frequency="0.12" /replace="t" variation 27322 /frequency="0.16" /replace="t" variation 27323 /frequency="0.16" /replace="t" variation 27395 /frequency="0.01" /replace="c" variation 27421 /frequency="0.21" /replace="a" variation 27680 /frequency="0.05" /replace="a" variation 27777 /frequency="0.03" /replace="t" ORIGIN 1 ctgttcacta tataattccc agcagctgct ttcatatctg gggcatactc acaggggtca 61 gtcaggaggg cactgtccta ggactgggag cgggaggatg tgggggtctc ccctttgagt 121 ttctgctatg atgtgattcc aattgatggg ccaacacacc tctgatacct tgtgttatgc 181 tgtgtactgc ctcaaagtga ataatagctt gggatttagt ttgtgtagtc taaggaaaat 241 actttgtgtt gaactagtca ggctgtttta ttgatggcca ttaaaaggcc ttgtgcttag 301 gtcttacaag cttttcaaag gcccaaagaa atgattcaga caaaaaaaaa aattagactc 361 caaaatacta aaagaaaact gcaaaaacag gtgaattaat ggtgaaagat ctgtaggaca 421 tagcagtaag gctaccacaa cccagctttt tgaggttgtc ttaaattaat gtgatatggg 481 gtgtaggtat gttaacatgc ttgataatgg aagagtgagg atacctgctt cttaaacagg 541 gcctgctcat ttttttctgg cctctagtac atttctttct ggcaaaactc aagctctgtt 601 ttcacggaga tgatgcactg agccatggca tccctaggtg gtttgattca tttctgcacc 661 ccggtgtcta gcaaagtgcc acgtgcatgt gtttaatcaa aatagcttgt ggttgtcaag 721 ctctttgtat tcttccctcc ctccctgtga tttgatttcc tgaaagtatc ctttccccaa 781 ggattatgga acatacactt gttaaacact ggacccattt tcatgatcat ttaaatgtca 841 tgacctttct gacaccttga tatggtttgg ctctgtgtcc ccacccaaat ctcatctaaa 901 ttataatccc catgtgtcca gggagggatc tggtgggagg tgattagatc atgggggcag 961 tttttcctat gctgttctca tgatagtgag tgaattctca tgagatctga tggtttaaaa 1021 gtgtttggca cttcccccct tgctctctct cctgctgtca tgtaagacgt gcctacttcc 1081 acttccacca tgattgtaag tttcctgagg cttccccagc catgcggagc tgtaagtcaa 1141 ttaaatcctc tttcctttat aaattaccca gtctcagata tttctttata gcagcgtgaa 1201 aatagactaa tacatgcctc ttgagatcct cacagcaatt ggtgccttta gacctcttca 1261 ttcacacttc actcatgtgt tcttccttcc ccaggtagac gcaccctctg aagatggtga 1321 ctccctcctg agaagctgga ccccttggta aaagacaagg ccttctccaa ggtaacaggg 1381 ctgagtcacc ccagggtccc aaggccggcc ttttctcaca aatagctgaa ctcctccact 1441 ctcagatcca ggggccctgg actatctccc attgtatgca aaaatatttt atttccgttg 1501 acacattact ctttggggca gcttgatggt tttattaaat tttggaagga ggcttcagcc 1561 ccagtaacag ccaatgcctg tttgctttcc caggtcacct tgactgtgct acagtagaga 1621 cctgggaaat ggtgggttcc agtgctgtgg ccaagctctc cccagtttca accccttcca 1681 ggccttgctg tccattttta ctccactgtc accacatgtt caaattcttg ctttctgctc 1741 gagtcagtac tgctcacctc gttccaagag atctgggtct atgacactgt gggtgacacc 1801 ctctgagcat cttttccgag ctgtctgtgg gtacctgaac ctgcccccca acctggccct 1861 tgccctacct gccccgacct cagcgagtct ggcccagtct gtccctgctt ctcccctctg 1921 gccccaagtg ttctcaaata tgcccccgcc tgcctgtctg tcactgcagc tggcccagcc 1981 ctcatcctct ctcccatgaa cctctgtggt ggcctgctct ccctggctcc cctgtctcca 2041 gtttatgttc cacacaggtg ccaaaatgtc tgcaaaaaat ggagatttaa catacactag 2101 cccttggctt aaaacctgta catgcttctc tgccacctgc aaatgacagt cccatttcct 2161 cagcaaacct ctgcatgttg tgggaactta tggcttctca gcctcccact cggaacccac 2221 ctctggttta tgctccagaa catgatgttg ttggaccctc ccctccacct cctccaggct 2281 gagttagcct ctgtctcccc tcctgccctg ggcatggctc ttccagtaga cacccccaca 2341 tcacagtcta actctgtgtc cacattccct gcaactgctg agctcctgga gccaggccct 2401 gggaaccttg ttcctgtttt tgttcccaga gccaaataga tatttgatgt atgattgttg 2461 aatgcagcag tgagtgaata aagacatgaa tggttaactg aaaacatttt atcaaaactg 2521 ttatttgtca tcagagcatg ggccggtttc caacagctaa catttaggag tgaccatttg 2581 ccaggcactg ttctaagccc tttgcatgtg gccattcatt tcacccacat agcgccatca 2641 atgacatgct gtcactgcat tgcttgtcaa aagggggaac tgaggcacgg aggctgagct 2701 tttactcaac atgccatcta tgttgaggga cttctgactt ggatagccat tcaactgcga 2761 gcactatgga ggccagtcag gcctggccct gccttggaat ttctgtgtta ttcagggaca 2821 taatggggtt tgtgttgatt tttgttggga gtgtgtgggt taatctaggt gcaaccctca 2881 cctccttccc ttctgatgtc ctcactccca ttggtcatgt gacccttaac gcccatccca 2941 agctcagtgc caattccttg ccccagggtc ctggggattg acatggatcc caaaagcccg 3001 ctgctgagag gacagggcca ctcccacccc cctgactgtt tcccagagca gctctggggc 3061 agaagtaaac ttggacccag ggggcataac cctttgccct tttatagtct attagaggag 3121 gatgaggtct gacatcagct ggttcattgc cccttgtgcc ccttgagcac actggggccc 3181 agggagagtc acatccctgc cttgtggtac aggccaccgg ccctggacct gtgattaaac 3241 attgtccaca attaatttgg aattattatc tcgtgataca ctccataaag ttcagtcaca 3301 catcttcttt ttcttctccc ctgcctaatg atcagacaag ccaggtcttg tgactaaatg 3361 aaccgacagc tggcagtgtt catctgattt tgcaatgccc ttattttgtt gttgataaac 3421 taatgcaaat agctggttgg cctggaactg gtgattggga aacattttaa cccttctttc 3481 cttcctctct atcctaaaga cttaaaacac acttcacgca gtcacagaaa gagctcatag 3541 accagactgc ggggcttcaa aggcttctat cttatttaat catctgtaaa tagtttaaag 3601 gtaaatatgg taataatact agtattctag actattttgg gaagccagct gatgtgaata 3661 aagggtcaga gttaaaagat attgaaggaa tgcagtttta ctgctctgag gtaggtttca 3721 aggcttgagc caggcttaga gatctttgtc ctgatactgg ggataaagtg aagagaatat 3781 gaatgggtat gtctcgcatg gttagaaaat cttttttttt cctgtatttg tttaaaaagc 3841 attttgtaac ttaaaaaaat acctatacac cttttttttt tttgagatgg agtctcactc 3901 tgtcactcag gctggagtgc agtggcacca tcttggctca ctgcaacccc cgcctcctgg 3961 gttcaagcaa ttctcctacc tcagcctccc cagtggctgg gattacaggc atgcaccacc 4021 acacccagct aatttttgta ctttttggta gagatggagt ttcatcatgt tggccaggct 4081 tgtcttgaag tcctggcctc aagtgatctg cctgccttgg gctcccaaag tactgggatt 4141 acaggggtaa accaccacac ctgaccataa tacatcttaa atagaacatt ttccagctaa 4201 tatttaaatg actgcatgtc attagaatct gaatgagtgt tgtgttaaaa tattttgtgt 4261 tttcatattt atttacttac ttatagctac ggataagaat ataggcaaat ttaatctccc 4321 gtaaaaatta aaaggcagat gttttcaaag cacagaatta catggtctac tctagacatt 4381 gctcctaagg ttgagcagag gggataagag ctttttctct tttttccttt cctctttttt 4441 tcatacaaag ttcgttgtag atattttaga aagtatagaa agccccgaca aggggaaacc 4501 cactcaaccc aattttaatg ttgttgtcat ttcttttagt ttttttgggt gcatttctat 4561 gtagctatat cctattgtac aagcaattta ggatcttgca atataaaatg aaggcatgac 4621 ctttgagctg gccaaaagta tgggctgatt tttgcaaatg ggtcctggca gcaggggaca 4681 taagtgggga accaatcccc acacaagcag aggtgagctg gcttaggggc gagtgcatag 4741 ctgactttgg atgtagacta gatttgggga aatttaaatg gggtccaaga ctggaaatgt 4801 gtaatgggac agaaggtaga aatgtttaaa atcttaagtt gttgagtttg ttctcaattt 4861 tgtgaaaact ctttatccct ttttgttccc caccccattt tctaaccaga agtcaaatat 4921 gacaacattc atgatgtaga aaaaccagtt catcagtgtg acttgtgggt gagggtgggg 4981 acagggccgg tgttggtata tttagtttta gagatttgct ggaaaagtaa catttttgct 5041 tttgtctttc tttcgttcct ccatttctcc agaagaatat gaaagtgtta ctcagactta 5101 tttgtttcat agctctactg atttcttctc tggaggctgg taagttaagt atttctttgt 5161 gttcttgtct gctaagaaaa tctgttattt agaatacatg aagtaccttc cctaacagag 5221 tcatttctca tactcgtctc tgttgaatct ctgggcacag agcctcctgg tcatagacct 5281 gtactgctgg aagttcctct cagcatcttc gtctcattct ctcccatata gagtgggaaa 5341 ctgaggccta gtgaggctga gagcccaagg tcatgtagct agttttggaa caaaagctaa 5401 aatctaggtc tccaatctag gtccaggcct ctttccactt ggctgctggt tgaaagtgtg 5461 atatgggaaa ttctgacttt catttggagg agatattatg tatagtcttt atgaacccac 5521 agctggaagt catcaagata cactactttt tctgtttctt tccatttctt cattttctct 5581 aatcttttct ctttttgcca ggtgctagct actggggata cagcagggaa cagtgcacac 5641 agaaatacct gcctgcatag ggtttatatt cttgtagaag agagagataa cagataagta 5701 gacatatatt gtgtcatatg atggcaagta tagggaggaa aaaagagtat aaggttttgg 5761 cattacagtg ggcagaaggt taattttttg aatgtggcca gaaaaaaacc tccctgagaa 5821 gctgactttt gagttgacct taaggaaggg gaaaagagag ctatttggat atcagattgg 5881 ggtgtggaaa tattccagtc agcatgtgca aaggcccaga ggccaagagt atttggcagg 5941 ctttcagaat aaaaatatca gcatgtctgg agcatagtga gagatgaggg aagtcataag 6001 ggaccaggct gtctgggtaa tggggggatg gcagagggtt gattatatag aatgttgcgc 6061 ccttttttag ggtcttggct tgtagtctgg ctgggatggg aagacttcag ggttctttgt 6121 ttaagaccag agaggtgatc tgacttaacg ttttgattcc tgttttgaga atagatccga 6181 gggagccaaa gagagaaata gagaagccag tgaagaggca agccatgatg atggctttct 6241 ctaggcaaga aatgttgatg gcttgtcaaa gggtggcaag gagaagtgag aagtagacaa 6301 attttgaaat attttgggaa cagaaccaag agggatttgg agttgggtca gatgtgagat 6361 gtgagggaaa gagaagaatc aagaattatc tcagggaatt ttggcctgcg caaacgcaag 6421 gtgaaattgc cattgatgag atggggaaga tcaggttttc agactggatg tgttaagttt 6481 agctgtccat tagatgttta aaaggtgact ttgactaggc agtctacagc ctgagggaaa 6541 ggtctgggtt gaatatataa aattggagac ctcagcaagc ggctggtatg agaaccatga 6601 gactgaatgg gatcatggag tgtagttagg aaagataaga actttaagga ctgagccaga 6661 gattgactta aattccttgg tccagtgagt tttctcccct ttgctgaggg gctccatgtg 6721 tgttggagca taccttcaac attaaggctg tttaaggcct tagccttcac ttcctgcttg 6781 tgtatgacct cagagtcatc cagaaatgag agcctggtgc cttctatgca atttcctggg 6841 catgcacaca gccctgcata catgcccacc cttctgggtt ccccaggaat gtgtcagagc 6901 ttttcaaagc cctctggagg ttatggctct ggtattgcag ctttaggcag ttgtaaaaaa 6961 caattaacac tgagtttttc cagcaaacgc cttggggata gtgcttttgc tgtggagctc 7021 ttggtgaggt caataacacc accaccctat gaatgtgact ttgaggacct gccagtcaag 7081 tcaaagagtg gcagtgctct ggaaatggga cttttcgagg agctccaaac cctctctctt 7141 cttgcaagcc tgctggtttt caaagccttt gtgtctgcaa agctcttgat attcatggct 7201 gttttagagc tgggaagagt aggatggaag tcatttaagt tataaagcta caaaccctgc 7261 tgatccgtga tttggcatgt ttctgtttgt ttccttattt tctagtaaat gctcttctgg 7321 ttactgcaag cctttgattt ttgaaatttt ttgccagtct ttttgttgcc tttatggagg 7381 aatgatttat gagaccccca ctccaccata ttggaaatct tgcaaattca atttctttga 7441 atagaaaata gtattaatag atatagggca atccaggcta tctacttctt ctcaagggag 7501 ctttaatagt ctggaaaatt tgctcatttc atttacgtta ttaaatttat tggcataaca 7561 ttgtttataa tattccctca ctacccttta caaattattt aaaaaagaga tgtcatctct 7621 tttttttcct gattagtctg gctaaagatt tatcaatttt attgattttg tgaaagaatc 7681 tgcttttggt atctttgatt tttcttcatt gttcttctgt tttctatttc attgatttcc 7741 tctctgatct atattactat tttcttctta cttctgttat attaattatg ttttttattt 7801 tctgtatctt accatatttt gacattctgg aagatgtttc atatctaggg agagactgct 7861 ccaccagggg ctaagcagtt cctaggtgtg ttgtggacag cttacagctt gcccttcatg 7921 tgagactgct tgacccaaga tggtacccca ctcacctcct tatccaactc tcacacaccc 7981 aaaccaatgt taccccagcc tcaatcaaca cagggctagg taccagagaa ctagggacag 8041 cctctatgcc caaagcctgc aaaaatggtt caaatgggcc aatctgaaac tgtttatgct 8101 gccctgcctt gcctttccca tgggaacccc agtaaagatg ctggcctagg ctttcctttt 8161 gtttctgctt ctgcctccta acccaatctg gtgattctcc ctgtggtttt gcgtggtatg 8221 gcacacccct tctgtccgaa ccactaagta atacaaatct ttcaattgca ttagtctctg 8281 ttttgtcact cagtcacctt cgtaaatgaa gacccaggca tagaatctct gcttgctgct 8341 tactttggaa ttactttgtt ctttttctag tttcttaagg tagaagctca agtcatcaat 8401 ttgaaatttt taaaaaatat ataggcattt aaggctagca gtttccctct aagtactgct 8461 ttcattgaat gccataagtt ttgatatgtt atgttttcct tatcattcag atacaaatac 8521 tttatattct ttttgatttc tttgactcat gagttattta ggagtatgtt aattttcaaa 8581 tatataggga ttccttggat atctttctat tattgatttc taatctaatt ccattgtcac 8641 cagagaataa gttttgtcta atttgaatcc ttttaaattt actgagtctt gggttatggg 8701 gaagaatatg gaaaatttgc taagttttat gtgtgcactt taaaaagaat gtaatgttct 8761 actgttgttg gttggaattt tctgcaaata tcaattatgt caaattggtt gatagtgttg 8821 ttcaaatctt ctatgttgtt actgattatc cgtttaattt tattgcttgt tctatcggtc 8881 cttgtgagtg gggtttctct agtttcttgc agaaccagtt tctctagttc ttgcagttct 8941 gtcagttttt gcttcatgta ttttgaagca ctgttagcag ctacataaac atttggtatt 9001 attgtgttcc tgttgattaa tgacttcttt atttttttaa aatttattta tttatttatt 9061 cattcatttt tgggacaaaa gtctctctgt gtcacccagg ctggagtgca gtggtgcgat 9121 ctcggctcac agcaacctct gcctactggg ttcaagtgat tcttgtgcct cagcctccca 9181 agtagctagg attatgggtg cccaccacca cacctggctg attttttttg tattttagta 9241 gaggtggagt ttcaccatgt tggccaggct ggtctcaaac tcctgacctc aggtgactca 9301 cccgcctcag ccttgcaaag tgctgggatt acaggcatga gccaccacgc ctggccgact 9361 tctttatttt tatgaaatgc cccttttttc ttgtaatatt tttactgtaa aatctacttt 9421 gataataata gtcactcaag ctttaactaa ttaattttta ttaaggtata gttgacaaaa 9481 tcgtgtatat ttacagtgta caatgtgatg ttttggtata tgtatacatt gtgaaatggt 9541 taaccctagc taattaatca aactttcttt tcatgagtgt tagcctggca aatatttttc 9601 ttttcttttt aatctatttt tacctttatt tataaaatgt ctgtatgtag gtgtatgtgt 9661 ttatgttagg caccacatag ttgggccttt ctttagccaa tctgatcatt tccgcctttc 9721 aatgagagtg tttagactat ttgaaatttt agtgtgatta ttcatatatt agggtttaat 9781 tctgggatct tgctatttgt ttttctattt gtcccatcaa ttctgttatt tttttctctt 9841 tttttgctgc cttttagatt aattggcatt tttaggattc attttatttt gctttttggc 9901 tttttagtca taactgtttg ttgtgtatgt gtttttttaa tgactgctct ggggcttaaa 9961 tagccatctc taagttatct ctgtctgcct tcaggtaaca ctatacagtt tcacatatag 10021 tatacaaagt taagagtata tacccatttc tcctttcttg aactttgccc tattatttcc 10081 atatatgtta cttctttatt tgttttaaac tttatagcat tttattattt tttatttaaa 10141 cactcagttt tctttaaaga gatttaaata ataagaaaga tgatcttata attacccatt 10201 tttgttgcta ttcattcttt tgcgtagatt cattttcatc ttataatatt gtgctttttg 10261 aaggaattaa atatttcttg taatgcaggt ctactggtga tgacatttta cagctttggc 10321 aaatctgaaa aagtcagtat tttttcctaa attttaaata tattttcatg ggatatggaa 10381 ttctaggtag actttttctt tcagtacttt aacgatattg ttttgctctc ttctggcttg 10441 tattgttttt ggaaagaaag ctgcatcatt ttttgtcttt gtcctctgca ataattgtgt 10501 catttctccc gggctacata gaagatttta tctttgtcac tggttttaaa caattttatt 10561 attatgtgtt tgtagtttgc tttatgtttc ttttgcttgg ggttcattgt gatttggggg 10621 cctatgtata catcattttt gtcacatctt gaaaaacttc aaatatgttt tctgttttcc 10681 acatttttct tcttcagtga ttcatattac atgtattgaa gttgtcctaa gtaaaataat 10741 tccctgccca ttttattctg ttatttttgt ctctgtgctt aattttggat aatttctaat 10801 gctgtgtctt caagttcact catctttttt tttcctgcag tatcaaatct gccgtgaatc 10861 ccatccattg ttttttgtaa ctcaacatta ttgttttcat ctctaaaagt tttttaaaat 10921 ctctttcatg tcttcactaa tcatgtttga tctttcctgt agcatcttga ataaatggaa 10981 tacaatagta ataaactatt ttaattttta aatttattag gcctattgtc tgtgtcattt 11041 ctgggtcagt tttgactgat cgattttttt cctccttatc gttggttgta tgttactgct 11101 tctttgcatg cctaattatt tttttggatg ttagacattg tggattttac catgttgggt 11161 gctggatatt ttcgtattcc ccagaatgtt cttgagcttt gttctgccac atgattgtta 11221 cttggaaatg gtttaatcct ttcgggtctt gcttttaagc ttaattagga tcaggaaaaa 11281 gtttattctt ggcctaattt tccctaatga ctgagtcaga acccttctgg gtactctgcc 11341 tgatgcctta tcattaatga ggctttccac cctggctgtt gggaacagca actgtttcca 11401 gcattgggtg tgctccatgt gttactccct ccagttcgtt tggtagtcct ccctctagcc 11461 ttgggtcatt ttcttatatg cttacactga ctgatactca gctgaaaact tgggggagac 11521 tctcagttat cccaagactc tttctgcttg tcgttatgca gctctaagta cttgggtact 11581 ctgccctgca aacttttcta cccaggttct cagctccatc tcctcaactc actgggcttt 11641 gcctgtgttt tttctcggca atgtcatggc ctagctgtaa ttttggacac ctcctttctt 11701 ctccgtcttt ctgggatttc tctcctttgt tttctgatgt tcaatgtctt gaatactgtt 11761 gtttcatata ttttgtccat tttttagttg ttcatgtggg aaggtaaatc cagtttctat 11821 tactccatct tgtactgaaa ggcatgtctc tcctcctaca ttgtccccac tttttagatg 11881 agtgaaaagg gggtgaagga tgttaaataa cttgccaggg gtacagcaca caggcagtaa 11941 gtgatgcagc tggacttgaa tatgcttctc agactcccca gataatgatc ttatcacaag 12001 gctgtaaagc ttttatatgt aatgtgaatt gatgtattta ataatcaatg tgtttcttcg 12061 tagatattaa atcaagacac actggcagat ttttatgtaa attgcttcca cccttcttcc 12121 ttttaaagat aaatgcaagg aacgtgaaga aaaaataatt ttagtgtcat ctgcaaatga 12181 aattgatgtt cgtccctgtc ctcttaaccc aaatgaacac aaaggcacta taacttggta 12241 taaagatgac agcaagacac ctgtatctac agaacaagcc tccaggattc atcaacacaa 12301 agagaaactt tggtttgttc ctgctaaggt ggaggattca ggacattact attgcgtggt 12361 aaggtaagag aggaattagt atgttacaaa catgttctag tttcctgcag ttgttaagga 12421 cagaaatact tttaataatg cttaacttac ctattttatt ttattttaga aattcatctt 12481 actgcctcag aattaaaata agtgcaaaat ttgtggagaa tgagcctaac ttatgttata 12541 atgcacaagc catatttaag cagaaactac ccgttgcagg agacggagga cttgtgtgcc 12601 cttatatgga gttttttaaa aatgaaaata atgagttacc taaattacag tggtataagg 12661 taattttatt ttaaatatga catttcactt ttccagaaaa taaaatagtt ccctggacaa 12721 tagaatgtat ctgcaaagta cctttttatt ttgtatattg ttttctcttt aatggtgaaa 12781 cttgataggg aacctaaaaa gaattgtaag actgcattca cttaatttga agcttaacta 12841 gaaatttgtt tgctgttgtt tttatttaat ttaataagat gtaattgaga aaagtactag 12901 aaatagatgt ttaaagagaa ggctgattat aagcttaagg tattgaagat gtaactattt 12961 attacaaaac atactatgtg tgttttattg aagatatggt cttcaaataa cctgctagtt 13021 tccataactg tctgaaaagt gggttgacta gctttccatg gaacacccca tgttttggta 13081 actttaatct acctagtctg atggaactta aatggggaat catcttgtag agcttaagac 13141 gtactaaata cgtaatatca atgaagtgca gtattgttaa gaaactatat agtgttaaca 13201 tttttttcaa acatgttttt cttgcaaaat aaattggcct tcacttcata gtacaagtct 13261 catagacttg aaaacttaat gtcataggaa tatagttaac tgtttccaaa aagccagtat 13321 taaaacttac tatatgtaag gaacttttcc agtcactttc taaaaatata acatttgcta 13381 aggtgaaaaa aatggagctc ctttggcggt agattgggga aagttattgg ttattggttt 13441 tcaatgcttc tctctccctt tatctaggat tgcaaacctc tacttcttga caatatacac 13501 tttagtggag tcaaagatag gctcatcgtg atgaatgtgg ctgaaaagca tagagggaac 13561 tatacttgtc atgcatccta cacatacttg ggcaagcaat atcctattac ccgggtaata 13621 gaatttatta ctctaggtga gtcatagctc cagccctaaa aggtttagat ctgggaaggt 13681 ccagagactg tgattctaat actactttca ttatccatga agaaaccaaa tccaagacga 13741 cctcaatgat accacaaaag tcacatggct ttagttttgt ttttttgtta ctaaatacta 13801 tgtaatgttt ttccattcct gcttcagatg tagttctaat taaatagaga cattatgagc 13861 tgtgttttcc aactgattta agagggttgt tctttggcat ggctaaaaat ggttcttact 13921 gaaagctctg gggctccctc tggctggtat atgggaatgt tctgagagcc tgcacctggg 13981 gaatctcagt gagtgtcagt gtctagcagc aagcatcggt gtggacacta atgagctttg 14041 gaataagtca catttccaga atctacctcc tgttcattct gtgttaggtg ttaacctctc 14101 taaccctgtt tcctcttctg taacaagatg atgcaatctc ccaaggttat tgggaagatt 14161 agagatatgg ggtacacgaa acttgtgtac ctggtgcaaa gaaatgcttg gtgcaaaaca 14221 gctatgcaat taataggtgt aggatgattg ttcttgttaa ttttcttgtg tctttcaatt 14281 ctgcgttaac catgtttcat attgaaaact atatcacagc aaaatgaaac aaaatgcaca 14341 aattgccagg ggatagtcag aatgctcaaa ctttttgtaa atattgagat tttgtaagat 14401 ttatgtaata aaataagagt tattccaatc agaacttttt tgcaggttat aggggtgact 14461 attagtagtt atgctgggac aacaggtata aattgggact atcccaagca aactcagaat 14521 atgatcaccc tataaatagc ttcacttttc cagttatata atactttatt ttcctaaaaa 14581 tatttttatt aaataaaagt taattccttg ccatggtccc acaggcatca gtgaatccca 14641 attttcaatg gtctttgtat caaaccatgt tcttgagttt ttagcagcct gtcattgggt 14701 agctctggtc tgtctttcct gaaacatagt aacctaacca gcaagtagaa cttgagagag 14761 aactgggcac tggggactat ttaagctagg ttaagtgttt tttttttttt tttttttttt 14821 gagatggagt ctcgctctgt cacccaggct ggagtgcagt ggtgcgatct ccgctcactg 14881 caagctctgc ctcccgggtt catgccattc ttctgcctca gcctcccgag tagctggaac 14941 tacaggcgcc cgccaccacg cccggctaat ttttttgtat ttttagtaga gatggggttt 15001 caccgtgtta gccaggatgg tctcgatctc ctgacctcgt gatccgccca cctctgcctc 15061 cttaagtgct gggattacag gtgtgagcca ccgcgcccgg ccaggttaag tgtgtttttg 15121 atattctctg tttccttttc tgatcccatt tgtagaaaca atatactcta ctcggagtga 15181 ggtaatattt tgttttcttt ccaaggccca caccaatgat gcctagcact ttttgttcac 15241 tcaaggattc aaaaatattt attgagcatt tactatgttt caggaactgt aataggtata 15301 cattagggaa aaaaacagag aatatcctac cttcatggtg ttcacttttt ttttgattgg 15361 gggaataccg agtgctcaat tttatagttt ctcatagttt cttcatggcc acagataaac 15421 ccctgaaacc aatcttttca taaataagtc agattaattt ctggggctcc ttgatacttt 15481 tttgcctatt ttaataaatt acagcattat tccataaccc tgtagttctc actattgggt 15541 cattaacaca gtcattaaat gcaagcaggt ctagtattga ctagcccttc tggccaataa 15601 cacccaattc aaggaagtga ctttccacta ctctcgcctt tgctgacatg ctttcactta 15661 agagaggcat ttgtctgggg acccagggtc ctggtgatgt gtgtgttttt cagtagcacc 15721 ccactctatg aattcggaag gtctagctct accccgggat tcacagtgtg ctgtggcctc 15781 tgcctcagct ttcttccttc actttctgcc tcctgtctcc tggcatatgt gctttgaaca 15841 cttgatggaa tatctggcca gaagtcattt agtatgtttt gctaagtgtt gtcgtcactt 15901 gagattctga tctataagag actgacaaac cttatggatg tttttctttc agaggaaaac 15961 aaacccacaa ggcctgtgat tgtgagccca gctaatgaga caatggaagt agacttgggt 16021 aagtgggctt cagtgagggt atgctggaat cggttttttt tttttaaaac ataagagtaa 16081 gataaattgt atctttacta tatataatct aagccattta ctgtataaat ctatcaatgg 16141 agggaaagtg agacaaatta tatcttaatt ttttgtattt cttgcctcta tggcaaacat 16201 cttgccatgt ctgatatctc cagccctact tttctgtgaa cacttattac catgaaaaca 16261 ccaaccagac accaaggtca aaaggcctag gaaccagcaa tgccattgac tggtacagga 16321 ttggatttct ttcttttttt ttttttcaca gagttaaaat atttaatgac aaaaataggg 16381 tttgctgtaa aagtgaatca atacagtagg tgttacttat ctctgaatta aacaaaaatt 16441 atatttgaca tcttaaagaa cttctgaaga attgatcatt gtacgacaga catcagcagt 16501 gttacaattt caggactgga tttctcatga ccagatccaa gctttgagtc ggaagagtaa 16561 ggctacaggc cccaaagatg gtagtcattc tagaaaagta tttttccaag ttagtgaaca 16621 ttttttattc aagagtaaag aaagaacccc acaagcatct agctctgcac tgtttagtgc 16681 agtagttact aggcgcatgg agttatggac atgtacaatt aaattaagtc aattgattca 16741 tttagttaaa ttaaaaatta gttcctctgt cacattagcc atatttcaag ggcttaatag 16801 ccacatgtga caagtgacta ctgtacagac aagcacaaat atagaacatt tccaacatca 16861 ctgaaagttc tattggaaac cactgatcaa gagagaaaaa gtggttcttt gtgtcagagg 16921 acccaaaata ggttggcctt ggaattgtcc tctgtaatag taactgcatg acagcagtca 16981 agaaccatac agaggttaga aggtatatgc ttgtgatctg tgaattctgt acttggccaa 17041 ttctgtactt gttatttatg gtggaaggtg gtagaaagac attcttagac agaaacaaaa 17101 atgtcaaaac tcaaaattaa atatgggcca ataggctcta gaacaatgtt tctcaaccat 17161 ctttttttgt tttaaattgt tcccctttag agtctaaaaa gtcttcttcc acctaattct 17221 ctttcctgtc tttaaatttc agtaccacag ttatctttta tatttgctga tatactgtgg 17281 ccctttggag taccacaaac catgtaatat ctaaggtttt cttgcctctt ccccaagaac 17341 cagtttttgc cctgctggcc acagcccctg ttgaaaatgc ctgccctaga agtgtgtaat 17401 tgagagctct gatgcctagg ctgcattgat ctctcaatct acaaaaaaaa gcttcaaatt 17461 aggaaataat tattttaatg tattatattg acagtggatc agaagcatat agtaccctgt 17521 cataggatta tcctgaaggg tgttaaacag gcaataagat ccaataccat tactcctaaa 17581 atgacttaga aaaataggga ttgagagata tttccttaac ttaataaata acatcagtgc 17641 aagccaatag tcactaatat tcttcatggt gaaatactat agaccttctc actaaagcca 17701 agagcaagac aaagatgccc atgtaaccac tattactgag cacagtctag aagtgcctac 17761 taatgcaatt gaaggaaaaa aacaaggtat gcttaccaca agggaaaaaa gacattttta 17821 ttattgtttc ctgatcatac caatcccaag aaaattcccg ggaaaaacta gaattaattc 17881 tgtataaatt agtcagataa taaattaaca tttagaatta atgttctaaa atataagact 17941 tgtttagcaa taaccagcta gaaaacataa taggaaacaa atgccatttg caccagtaaa 18001 tgtcttagaa gtgtccataa aatatgttag aaaaactttg aaaatatgtg gaatttataa 18061 gagaggaaaa aactaaaaaa accaaaaccc tgaatattaa tctcagaaaa actgaaattt 18121 aaagcatgca tccagccagg cgtggtggct caagcctgta attccagcac tttggtaggc 18181 caaggtggac agatcacttg aggccaggtg tttgagacca gcctggccaa gatgttgaaa 18241 caccatctct actaaaaata caaaaattag ctgggtgtgg tggtgcacac ctgtagttcc 18301 agctgctcaa gaggctgagg catgagagtc acttgaaccc aggaggagaa ggttacagtg 18361 agccgagatt gtgccactgc acttccagcc tgagtgacag agcgagactg tgtctcattt 18421 ttaaaaatgg aattaaataa tggatagagg gataacagtt tttaaaaagg aaggccgatg 18481 agcaccaagc taatgaaaag catgttgatt caccgtgaat tcaagaaatg tagatgaaaa 18541 cttaagtgac attttcttct ctcaaaaggc aatgtctaac caaaaacact tgttatctgg 18601 tggttttggg gaaaatcgtg ctcacataca ctattggaga gagggtagac tgacacagcc 18661 tcactaaaga gagggggtta gcttttaaaa tatgtttctt taattcaatc ttgcttctag 18721 attttaatac ttcaggatgt gtacaaataa ggctattcat taaaatatta atcataatag 18781 tgaaaaatta ggaaattgtg ttcatcaata ggaaatagtt aatcatagtg tatatgtatt 18841 atggaatgct aagcagccat gacagagtct attttggaag acaaatcatg tgggcccaaa 18901 ttcccaatcc acagtaatta caaaatagta ggcaaaaaga ccccatttca aaaactgcac 18961 atgttcacag agaagataag gaatgagacg cataaggtta ctaatggtgg ttttctctgg 19021 gtggtgggtt tagggtaatt ttcctttttc tttgtgcatt tctatatcta aaattttaat 19081 tcaatagcca tttattaatc tagatagatc agaaaaaatc aattaatgtt aagattaaaa 19141 atacattctt tgcaggatcc cagatacaat tgatctgtaa tgtcaccggc cagttgagtg 19201 acattgctta ctggaagtgg aatgggtcag taattgatga agatgaccca gtgctagggg 19261 aagactatta caggtatgta tgctaagagt tattcacatt ttgatgttaa atcccacgtg 19321 atattttata taaccttgtc ggttcagttt aaaagcaagt gttagttgct cctaaccttt 19381 gctgcctttt tttttttttt tttttttttt tgctaagcta agtagaattt ataagatctt 19441 gtacatttaa ggtaaaaaat acttgtcatt gtggtgcaaa ttacagacca cttagaagcc 19501 tttctcttac gttatacatg ttgcaacatt tcaacgaagc aattatcttt cattattctt 19561 catattcctc aagtagctta gaagagactc attaatgagc tcaagaatca ggcaatccac 19621 tgctctcgaa agcctctact ggtttcctac tgctcatcta tgggacaagg atctcctggc 19681 ttcccatgac ctctccttca caacacctgc aaagcacttt gtcatctgcc ccaatctcct 19741 cttgtttagt gtctcctctg tgccccatgg agaacacaat gcatttgtct acatttttct 19801 tcttggaagt ggtaattttt ttgctttctc tgctactgag cctgttactg acagtggtct 19861 tggggttata aaatctcaga ttagtgttgc cagcagtctg aatgttgtga ctgtgattgg 19921 gcagggtgat tatttcagtg gcaattttgt cacaaataag gaaatacaca gggtatacag 19981 gtcttatttg tagttgatgc aattaactta cacaagttta tttactctct ctctcgaata 20041 gtgtggaaaa tcctgcaaac aaaagaagga gtaccctcat cacagtgctt aatatatcgg 20101 aaattgaaag tagattttat aaacatccat ttacctgttt tgccaagaat acacatggta 20161 tagatgcagc atatatccag ttaatatatc caggtaaaca acaaactaat tgaaatgcag 20221 ttttgtttta ctgtagtaag attccatgac tttgaagttt gaaatgccat ttcctctgct 20281 tagaacacgc ttcacttcct cattacttgg gtaacttcta tttctctttt actcttctgc 20341 tgaactctct cttcttggaa gcttttctgt cctgctgcct gcccttaacc cagctctcgg 20401 cccaaagaga ggaggttagg gcctctgtat gtacttctgt agcaccatat gtcacaggat 20461 ctatggtact tcgttttctg tacttaacta taaattctgt gatggtggca accatttatc 20521 ttagtaatca ttctatttcc acagctaatg gcaagttagg tctggtacat tgtgggtacc 20581 caatgaacta cattgatgat gcatagggta agactaaata tccactttca aagaggacat 20641 cagaagtcac tgggtttcat gaattggtat aataaaacat aatattgaaa gtatttgtga 20701 aacattttaa ggtaatttgt ggtttaatta aacataggct attataattg cgtgcatgga 20761 agaatatctg aaagactcta taaattaact tctatgtatg tttaaatact ggcagcatac 20821 aaatagaaat tacatttaaa agataacatt tatggtagca tcaaaaatca tcaaatactt 20881 aagaataaat ctagcaaaag ctgttcaaaa cctctgtaat acaaactaaa aaatattgag 20941 ataaattaga gaagaactaa atggaaggat atacaatgtt catagattga aagactcgat 21001 attatgaaga tatcagttct tccccaaatg aatctatgga ttccaaaaaa tttcaatcaa 21061 aatctcagca gtatttgtac aagtgagagt cagtgtttgt atgggtgtgt ttttgtggac 21121 acctgtaaaa gtcataggga actgtaaagg accaagtata gtcatggtgg tcttaaataa 21181 gaaaaataaa tctggaggat tattactaca gacatcatga tcttgtatga agcgacagta 21241 cttaagaccg taagtgtgaa ctatcatttg ggccagctgg atatttgtct ggaaaatggt 21301 ataacttgat ttctgtttta tatccaaatc atttaaattg gaaaagtaaa taaagctttt 21361 agattccctt ttctggatgc ttttacatgg ttcctgatat ttagagggta ctttcttttt 21421 cttccctctt tcttcttctc tagccccctc cccatcacct actccatctg ctccccagct 21481 tcctctttaa ttattggata actaagtaga gaaggaggcc aggagaatgt ggaaatgtga 21541 aacttcccta agcctccacc ttattcgctt tccaccagtc tttaacttta cccaatggac 21601 tctctgacct cagggaactt ttgtaggctt ttgagtgatt ttaacttttc cctgttttac 21661 tgtggaatgc tctatcctgt ggtcttcggt attatttccc atgttattgt atattatgct 21721 atttaggtag aaacttcata gaatgcacct tagttttatc attgctttgt acattagtat 21781 ccattacaaa gtgataataa tgaatgagtt aatattgtct gaatgcaggc cattcccaga 21841 tatgggctct ctgagacgaa gatatttaat ttgctgtgct caaagtttta attctttttg 21901 gttctaatat tttttctcct ttttttttct ttttgctata gtcactaatt tccagaagca 21961 catgattggt atatgtgtca cgttgacagt cataattgtg tgttctgttt tcatctataa 22021 aatcttcaag attgacattg tgctttggta cagggattcc tgctatgatt ttctcccaat 22081 aaaaggtata attttgtatt ccatgcagta tttcttgttg gagataaggg atagttagga 22141 gatgtagaag atgactaaga gggtttttac taagagggtt tctaaaatga aaagtggcat 22201 atacaagaat actagttatt cttacacaga attatagttt tagaactcat taggctgaat 22261 atcattgttt tctaagttcc tgcctcaaca ttcatattgg tagaataaac aggtatttag 22321 agcatctgtt tataaattca gttatgcaca agccattggt aggccttgct ctgtgatgaa 22381 taggacagac agagatcata ccttaatgaa agaaatgaaa tgactagatc ttcatgcatc 22441 agggaggttc tctctctctc ctttgtttaa actttgcgaa aaaaaaaaaa ggaataccac 22501 aatatctaaa aaaaaatgaa tggatagaat tcagggctga gacctctggg gaagaagatg 22561 aggacaggga gactttaagg atggctctat actaagagta tacgaggcag cctccaaata 22621 gaagaacaaa tttgcagtaa aacacaagaa atagaaacct tgtaagagat gaacactttt 22681 taaagggatt atatttttgg tattgctgct tcagtcatgc cattgtataa aaaaagatga 22741 atagttcatt atgtaatgaa tgtttgtgat actgacttta tcaaatctct tatttttgcc 22801 ttgtggttct aaatacatta tgtttttcct ttagcttcag atggaaagac ctatgacgca 22861 tatatactgt atccaaagac tgttggggaa gggtctacct ctgactgtga tatttttgtg 22921 tttaaagtct tgcctgaggt cttggaaaaa cagtgtggat ataagctgtt catttatgga 22981 agggatgact acgttgggga aggtatgtgt gtaatggaac agagtaaagg cttattgttg 23041 taaaactact tagtaaaatg tggattccat ctttctagaa gatcgtggca taggggtata 23101 tgtttcacaa ttttaagaac ctcttcagaa gtgtatgatg atttttacat ttattaaatg 23161 catttacttc tctcatattt tgtcagagca ataattaagt gattttcatt tagttttgaa 23221 aaacttaatg actagttaaa cccaacagtt gctttacaac tgatacaatt aaacaggagt 23281 ggtagagatc aaatgattga ataataagtt tttaaaattc caacaaagtt ttctgagttc 23341 taaatgaaat atttgtcttt tgagggccaa tttttgagtt agtctataaa atgggaggtt 23401 tgcagtggct catgcctttt atctcagtac aaccctggga ggccagggtg agagggtcac 23461 ttgagcctag gagtttgagg ctgcagtgat ccaagatcac gccactgcgc tccagtgtga 23521 gcaacagaac aagagactgt ctcttaaaat taattaatta aaaacatggg aaactccttt 23581 aattttaagt aagacaagaa aaaggcatta ggagccatac ggttgtgaaa agccttgtgt 23641 ggctttggtt caggagagaa tgatgataaa tagaatttta cttactatat tgtgcttcct 23701 gtttttcaga cattgttgag gtcattaatg aaaacgtaaa gaaaagcaga agactgatta 23761 tcattttagt cagagaaaca tcaggcttca gctggctggg tggttcatct gaagagcaaa 23821 tagccatgta taatgctctt gttcaggatg gaattaaagt tgtcctgctt gagctggaga 23881 aaatccaaga ctatgagaaa atgccagaat cgattaaatt cattaagcag aaacatgggg 23941 ctatccgctg gtcaggggac tttacacagg gaccacagtc tgcaaagaca aggttctgga 24001 agaatgtcag gtaccacatg ccagtccagc gacggtcacc ttcatctaaa caccagttac 24061 tgtcaccagc cactaaggag aaactgcaaa gagaggctca cgtgcctctc gggtagcatg 24121 gagaagttgc caagagttct ttaggtgcct cctgtcttat ggcgttgcag gccaggttat 24181 gcctcatgct gacttgcaga gttcatggaa tgtaactata tcatccttta tccctgaggt 24241 cacctggaat cagattatta agggaataag ccatgacgtc aatagcagcc cagggcactt 24301 cagagtagag ggcttgggaa gatcttttaa aaaggcagta ggcccggtgt ggtggctcac 24361 gcctataatc ccagcacttt gggaggctga agtgggtgga tcaccagagg tcaggagttc 24421 gagaccagcc cagccaacat ggcaaaaccc catctctact aaaaatacaa aaatgagcta 24481 ggcatggtgg cacacgcctg taatcccagc tacacctgag gctgaggcag gagaattgct 24541 tgaaccgggg agacggaggt tgcagtgagc cgagtttggg ccactgcact ctagcctggc 24601 aacagagcaa gactccgtct caaaaaaagg gcaataaatg ccctctctga atgtttgaac 24661 tgccaagaaa aggcatggag acagcgaact agaagaaagg gcaagaagga aatagccacc 24721 gtctacagat ggcttagtta agtcatccac agcccaaggg cggggctatg ccttgtctgg 24781 ggaccctgta gagtcactga ccctggagcg gctctcctga gaggtgctgc aggcaaagtg 24841 agactgacac ctcactgagg aagggagaca tattcttgga gaactttcca tctgcttgta 24901 ttttccatac acatccccag ccagaagtta gtgtccgaag accgaatttt attttacaga 24961 gcttgaaaac tcacttcaat gaacaaaggg attctccagg attccaaagt tttgaagtca 25021 tcttagcttt ccacaggagg gagagaactt aaaaaagcaa cagtagcagg gaattgatcc 25081 acttcttaat gctttcctcc ctggcatgac catcctgtcc tttgttatta tcctgcattt 25141 tacgtctttg gaggaacagc tccctagtgg cttcctccgt ctgcaatgtc ccttgcacag 25201 cccacacatg aaccatcctt cccatgatgc cgctcttctg tcatcccgct cctgctgaaa 25261 cacctcccag gggctccacc tgttcaggag ctgaagccca tgctttccca ccagcatgtc 25321 actcccagac cacctccctg ccctgtcctc cagcttcccc tcgctgtcct gctgtgtgaa 25381 ttcccaggtt ggcctggtgg ccatgtcgcc tgcccccagc actcctctgt ctctgctctt 25441 gcctgcaccc ttcctcctcc tttgcctagg aggccttctc gcattttctc tagctgatca 25501 gaattttacc aaaattcaga acatcctcca attccacagt ctctgggaga ctttccctaa 25561 gaggcgactt cctctccagc cttctctctc tggtcaggcc cactgcagag atggtggtga 25621 gcacatctgg gaggctggtc tccctccagc tggaattgct gctctctgag ggagaggctg 25681 tggtggctgt ctctgtccct cactgccttc caggagcaat ttgcacatgt aacatagatt 25741 tatgtaatgc tttatgttta aaaacattcc ccaattatct tatttaattt ttgcaattat 25801 tctaatttta tatatagaga aagtgaccta ttttttaaaa aaatcacact ctaagttcta 25861 ttgaacctag gacttgagcc tccatttctg gcttctagtc tggtgttctg agtacttgat 25921 ttcaggtcaa taacggtccc ccctcactcc acactggcac gtttgtgaga agaaatgaca 25981 ttttgctagg aagtgaccga gtctaggaat gcttttattc aagacaccaa attccaaact 26041 tctaaatgtt ggaattttca aaaattgtgt ttagatttta tgaaaaactc ttctactttc 26101 atctattctt tccctagagg caaacatttc ttaaaatgtt tcattttcat taaaaatgaa 26161 agccaaattt atatgccacc gattgcagga cacaagcaca gttttaagag ttgtatgaac 26221 atggagagga cttttggttt ttatatttct cgtatttaat atgggtgaac accaactttt 26281 atttggaata ataattttcc tcctaaacaa aaacacattg agtttaagtc tctgactctt 26341 gcctttccac ctgctttctc ctgggcccgc tttgcctgct tgaaggaaca gtgctgttct 26401 ggagctgctg ttccaacaga cagggcctag ctttcatttg acacacagac tacagccaga 26461 agcccatgga gcagggatgt cacgtcttga aaagcctatt agatgtttta caaatttaat 26521 tttgcagatt attttagtct gtcatccaga aaatgtgtca gcatgcatag tgctaagaaa 26581 gcaagccaat ttggaaactt aggttagtga caaaattggc cagagagtgg gggtgatgat 26641 gaccaagaat tacaagtaga atggcagctg gaatttaagg agggacaaga atcaatggat 26701 aagcgtgggt ggaggaagat ccaaacagaa aagtgcaaag ttattcccca tcttccaagg 26761 gttgaattct ggaggaagaa gacacattcc tagttccccg tgaacttcct ttgacttatt 26821 gtccccacta aaacaaaaca aaaaactttt aatgccttcc acattaatta gattttcttg 26881 cagttttttt atggcatttt tttaaagatg ccctaagtgt tgaagaagag tttgcaaatg 26941 caacaaaata tttaattacc ggttgttaaa actggtttag cacaatttat attttccctc 27001 tcttgccttt cttatttgca ataaaaggta ttgagccatt ttttaaatga catttttgat 27061 aaattatgtt tgtactagtt gatgaaggag ttttttttaa cctgtttata taattttgca 27121 gcagaagcca aattttttgt atattaaagc accaaattca tgtacagcat gcatcacgga 27181 tcaatagact gtacttattt tccaataaaa ttttcaaact ttgtactgtt atcctgagaa 27241 tctgttcttt gtccagtcca cagcttacct gcacatttgc acattcccag gcctcaacaa 27301 ggtgaggaga ccttctgcag agagttcttc ctgttgtggg gaagcaggtg gggaggagct 27361 ggaggagggg aggggagtgg aggtcagagg ctattggctt aacagtgagc cctaactccc 27421 ttcttctagc taaactctac tccctctgct catttgcttc taaaatggat taaaatgtga 27481 gccttgtcaa taactgttta ttaacttctt atcaatttac tattaactta tcactttacc 27541 tgtccaaaaa atgataaagg gaatatttgt atagactttt acattttaca aagcgctttt 27601 attttttcct ttgacccaga aggtgggcaa aattggtgaa cttgctgtcc aaaatgcatg 27661 ctctaaagct tgttaactct gatggtcaga gatgacaccc agtcagtgcc tccttcttac 27721 ctcacagcaa tgctaagggg caggtgactc tctcagtacc tggggagaag gggcaggtgg 27781 caggttggct tagagtctga gtccagtatg agcactgcct ccaccagcta cctggagtga 27841 aaccttaggc aaagtatttg agcc //