LOCUS AY280502 19655 bp DNA linear PRI 30-SEP-2003 DEFINITION Homo sapiens EPHB6 (EPHB6) gene, complete cds. ACCESSION AY280502 VERSION AY280502.1 GI:30230682 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 19655) AUTHORS Rieder,M.J., Carrington,D.P., da Ponte,S.H., Hastings,N.C., Ahearn,M.O., Kuldanek,S.A., Rajkumar,N., Toth,E.J., Yi,Q. and Nickerson,D.A. TITLE Direct Submission JOURNAL Submitted (21-APR-2003) Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195, USA COMMENT To cite this work please use: SeattleSNPs. NHLBI HL66682 Program for Genomic Applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu). FEATURES Location/Qualifiers source 1..19655 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" variation 361 /frequency="0.01" /replace="t" variation 489 /frequency="0.01" /replace="c" repeat_region 503..781 /rpt_family="Alu" /rpt_type=dispersed variation 523 /frequency="0.01" /replace="t" repeat_region 815..862 /rpt_family="L2" /rpt_type=dispersed variation 823 /frequency="0.02" /replace="g" variation 1131 /frequency="0.02" /replace="t" variation 1158 /frequency="0.01" /replace="a" variation 1338 /frequency="0.02" /replace="a" variation 1525 /frequency="0.02" /replace="a" variation 1549 /frequency="0.01" /replace="a" variation 1726..1729 /frequency="0.03" /replace="" variation 1962 /frequency="0.02" /replace="g" variation 2006 /frequency="0.01" /replace="t" variation 2077..2081 /frequency="0.03" /replace="" variation 2460 /frequency="0.06" /replace="t" variation 2500 /frequency="0.16" /replace="c" variation 2565 /frequency="0.01" /replace="a" variation 2674 /frequency="0.47" /replace="g" variation 2873 /frequency="0.04" /replace="t" gene 2950..18982 /gene="EPHB6" mRNA join(2950..3274,8942..9076,9907..10023,10646..10723, 11025..11217,11521..11585,11856..12636,13362..13517, 13847..14203,14368..14492,14793..14955,15495..15609, 15884..15936,16128..16247,16379..16626,16861..17034, 17704..17853,18101..18294,18417..18572,18683..18982) /gene="EPHB6" /product="EPHB6" variation 3003 /gene="EPHB6" /frequency="0.05" /replace="a" variation 3369 /gene="EPHB6" /frequency="0.20" /replace="t" variation 3450 /gene="EPHB6" /frequency="0.01" /replace="a" variation 3675 /gene="EPHB6" /frequency="0.01" /replace="a" variation 3775 /gene="EPHB6" /frequency="0.02" /replace="t" variation 3822 /gene="EPHB6" /frequency="0.01" /replace="a" variation 3916 /gene="EPHB6" /frequency="0.17" /replace="c" variation 4010 /gene="EPHB6" /frequency="0.01" /replace="t" variation 4061 /gene="EPHB6" /frequency="0.01" /replace="a" variation 4272 /gene="EPHB6" /frequency="0.12" /replace="g" variation 4405 /gene="EPHB6" /frequency="0.16" /replace="a" variation 4447 /gene="EPHB6" /frequency="0.02" /replace="g" variation 4506 /gene="EPHB6" /frequency="0.01" /replace="g" variation 4554 /gene="EPHB6" /frequency="0.08" /replace="t" variation 4750 /gene="EPHB6" /frequency="0.04" /replace="g" variation 4753 /gene="EPHB6" /frequency="0.08" /replace="a" variation 4972 /gene="EPHB6" /frequency="0.18" /replace="g" variation 5003 /gene="EPHB6" /frequency="0.02" /replace="t" variation 5030 /gene="EPHB6" /frequency="0.02" /replace="c" variation 5046 /gene="EPHB6" /frequency="0.02" /replace="t" variation 5378 /gene="EPHB6" /frequency="0.50" /replace="a" variation 5581 /gene="EPHB6" /frequency="0.02" /replace="t" variation 6079 /gene="EPHB6" /frequency="0.01" /replace="g" misc_feature 6255..6503 /gene="EPHB6" /note="Region not scanned for variation" repeat_region 6311..6601 /rpt_family="Alu" /rpt_type=dispersed variation 6551 /gene="EPHB6" /frequency="0.03" /replace="t" variation 6565 /gene="EPHB6" /frequency="0.04" /replace="c" variation 6761 /gene="EPHB6" /frequency="0.05" /replace="a" variation 7038..7042 /gene="EPHB6" /frequency="0.77" /replace="" variation 7119 /gene="EPHB6" /frequency="0.02" /replace="g" variation 7164 /gene="EPHB6" /frequency="0.01" /replace="t" variation 7314 /gene="EPHB6" /frequency="0.04" /replace="c" variation 7429 /gene="EPHB6" /frequency="0.01" /replace="c" variation 7873 /gene="EPHB6" /frequency="0.01" /replace="g" variation 8265 /gene="EPHB6" /frequency="0.23" /replace="t" variation 8337 /gene="EPHB6" /frequency="0.01" /replace="g" variation 8447 /gene="EPHB6" /frequency="0.01" /replace="g" variation 8482 /gene="EPHB6" /frequency="0.24" /replace="g" variation 9023 /gene="EPHB6" /frequency="0.02" /replace="a" variation 9118 /gene="EPHB6" /frequency="0.06" /replace="a" variation 9218 /gene="EPHB6" /frequency="0.01" /replace="g" variation 9234..9243 /gene="EPHB6" /frequency="0.24" /replace="" variation 9291 /gene="EPHB6" /frequency="0.06" /replace="c" repeat_region 9459..9818 /rpt_family="L1" /rpt_type=dispersed variation 9533 /gene="EPHB6" /frequency="0.22" /replace="a" repeat_region 9827..10199 /rpt_family="MaLR" /rpt_type=dispersed variation 9968 /gene="EPHB6" /frequency="0.01" /replace="a" variation 10182 /gene="EPHB6" /frequency="0.03" /replace="g" repeat_region 10200..10301 /rpt_family="L1" /rpt_type=dispersed variation 10304 /gene="EPHB6" /frequency="0.01" /replace="c" variation 10317 /gene="EPHB6" /frequency="0.07" /replace="a" variation 10789 /gene="EPHB6" /frequency="0.03" /replace="g" variation 10833 /gene="EPHB6" /frequency="0.08" /replace="c" variation 10866 /gene="EPHB6" /frequency="0.01" /replace="a" variation 10914 /gene="EPHB6" /frequency="0.03" /replace="a" variation 10924 /gene="EPHB6" /frequency="0.03" /replace="g" CDS join(11163..11217,11521..11585,11856..12636,13362..13517, 13847..14203,14368..14492,14793..14955,15495..15609, 15884..15936,16128..16247,16379..16626,16861..17034, 17704..17853,18101..18294,18417..18572,18683..18791) /gene="EPHB6" /codon_start=1 /product="EPHB6" /protein_id="AAP20939.1" /db_xref="GI:30230683" /translation="MVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPGGWDEV SVLDDQRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSL GVSGGTCRETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSS SAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCP AVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGK WMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCP CLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVC KECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNG VSELSPDPPQAAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQL RYYDQAEDESHSFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLP QGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQRKRRGTGYTEQLQQYSSPG LGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRGRREQ TVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGP LDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVAR LGHSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVL NAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGG DPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLED LPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV" variation 11423 /gene="EPHB6" /frequency="0.05" /replace="t" variation 11509 /gene="EPHB6" /frequency="0.01" /replace="g" variation 11809 /gene="EPHB6" /frequency="0.06" /replace="g" variation 11987 /gene="EPHB6" /frequency="0.01" /replace="a" variation 12054 /gene="EPHB6" /frequency="0.01" /replace="a" variation 12143 /gene="EPHB6" /frequency="0.04" /replace="t" variation 12185 /gene="EPHB6" /frequency="0.03" /replace="a" variation 12535 /gene="EPHB6" /frequency="0.01" /replace="g" variation 12666 /gene="EPHB6" /frequency="0.03" /replace="a" variation 12868 /gene="EPHB6" /frequency="0.31" /replace="c" variation 12980 /gene="EPHB6" /frequency="0.04" /replace="a" variation 13385 /gene="EPHB6" /frequency="0.04" /replace="g" variation 13432 /gene="EPHB6" /frequency="0.01" /replace="t" variation 13676 /gene="EPHB6" /frequency="0.10" /replace="g" variation 13687..13690 /gene="EPHB6" /frequency="0.99" /replace="" variation 14242 /gene="EPHB6" /frequency="0.04" /replace="t" variation 14289 /gene="EPHB6" /frequency="0.06" /replace="t" variation 14404 /gene="EPHB6" /frequency="0.01" /replace="a" variation 14649 /gene="EPHB6" /frequency="0.03" /replace="g" variation 14986 /gene="EPHB6" /frequency="0.23" /replace="a" variation 15403 /gene="EPHB6" /frequency="0.02" /replace="a" variation 15517 /gene="EPHB6" /frequency="0.02" /replace="a" variation 15779 /gene="EPHB6" /frequency="0.07" /replace="a" variation 15797 /gene="EPHB6" /frequency="0.05" /replace="a" variation 15852 /gene="EPHB6" /frequency="0.02" /replace="a" variation 15854 /gene="EPHB6" /frequency="0.01" /replace="a" variation 15875 /gene="EPHB6" /frequency="0.05" /replace="a" variation 15908 /gene="EPHB6" /frequency="0.02" /replace="a" variation 16295 /gene="EPHB6" /frequency="0.41" /replace="c" variation 16503 /gene="EPHB6" /frequency="0.06" /replace="t" variation 16609 /gene="EPHB6" /frequency="0.01" /replace="t" variation 16733 /gene="EPHB6" /frequency="0.21" /replace="a" variation 16773 /gene="EPHB6" /frequency="0.09" /replace="g" variation 16777..16778 /gene="EPHB6" /frequency="0.01" /replace="" variation 16793 /gene="EPHB6" /frequency="0.01" /replace="a" variation 16794 /gene="EPHB6" /frequency="0.02" /replace="a" variation 16817..16818 /gene="EPHB6" /frequency="0.72" /replace="" variation 17050..17063 /gene="EPHB6" /frequency="0.01" /replace="" repeat_region 17293..17532 /rpt_family="MIR" /rpt_type=dispersed variation 17360 /gene="EPHB6" /frequency="0.03" /replace="t" repeat_region 17533..17666 /rpt_family="MIR" /rpt_type=dispersed variation 18076 /gene="EPHB6" /frequency="0.28" /replace="g" variation 18652 /gene="EPHB6" /frequency="0.08" /replace="a" variation 18907 /gene="EPHB6" /frequency="0.15" /replace="" variation 18981 /gene="EPHB6" /frequency="0.02" /replace="g" variation 19012 /frequency="0.27" /replace="g" variation 19068 /frequency="0.16" /replace="c" variation 19497 /frequency="0.06" /replace="" ORIGIN 1 acaaagcctc aagacagttc agtgaagggc ctgagccctg tgaggtcatg cattgggagc 61 tataactaat gttttggaat aagagatagg ggactcagaa gactccttta tggcttttta 121 ctagaattct tatcagtgaa attatttgta aagctctttg tttatgacaa catcagctta 181 cattagctgt tctaagggga aataaggaag aagaaaattg cacatcctag gggagtgagc 241 aaagcccaag aaggaggcaa aaactcagaa aaaatgaggc agaaccaatc taggagcctt 301 cctatctcac ctggagtttt ctactcagca gttccttttg gttccaaatt tacataatag 361 attgttgtgt gccagaaatg attaattctg tgagccataa actttattag gtcctgccca 421 ttagcaatac tccagggttt tttttttgaa caagtcaaaa aaaaaaaata tatatatata 481 tacacacata tatatataga aagaaacagg gtctcactct gtcgcccagg ctggagtgca 541 gtaggacaat cttggctcac tgcaacctcc gcctcccggg ttcaagcgat tctcccacct 601 tggcctcctg agtgtctggg actataggca tgcatcacca tgcctggcta atttttgtat 661 tgtttggtag agatgaggtt tcaccatgtt ggccaggctg atctcaaact cctgacctca 721 agtgatcctc tcacctcagc ctcccaaagt gctgggatta caggcataag ccactgtgcc 781 catccacata gaaaaagttt aaatattatt ttttattgat tcattctata acacttctaa 841 gcacctggag tgtcccaggc accaaacaaa ttatagcaaa aaatttacat taaactttaa 901 aaaggaattc attactttgc tttttaatag ctgcaggttg cagcatactt taacaatgca 961 ttctatgctc tccacctacc attaaaactt ggtttgataa gacataggca attaggatgc 1021 aaagccgact aatcacaaat ttaaacctct ttgcatcctg agtatgacac ttcctttgaa 1081 aactagatgc ctctcaaatt ttattaacaa gacaaatata actaattaca caagccttga 1141 gcagcaaaaa cttcatttca tattatagtc acctaatatg aggtatatca tgaaatagaa 1201 aagaaggcag atatttttac tgttatgtca atacaggata cgttgcaaat tactacagga 1261 atttctgggt tttataaagt aacaactacg gtttggtttt gtccatattt ttattttaac 1321 ataatctagt tatgtgtctt ttttttaagt tttcaatata accatagatg tctagcaatc 1381 aggcatgtta atgtatgagt tacgtaattc cacacacaat gcaaattctg tttctttgca 1441 gaagtctttg aaagccttgg agataaccag aaaatgaagg aagccctcca ccactgagtt 1501 tcagggcaaa gggaagaaac aagataaagt agaaccgtca gtacaagtgg aattattaat 1561 gacgtccaaa tgcagtcatt aaatactatc agacttattt attgactcct gatattaaga 1621 gtgaacaaac ccctggccaa gtgggaactt gctcggtagc ctttatcttt ctatcactca 1681 ttcagtcaat tcattaaagc ctgtttgtct ctcccaggtg actcttactg agtttcattg 1741 ttttgtttat tgtgtttgtt ggctcataga tctctttcac aattttcttc ggcttctgaa 1801 tgctctttaa gtaccagttt tgatcagccc atttgcttta ataaacagga gagcaagatg 1861 ggacagggcg atacagggag aaaagggggc aaagggaatc gcaccgggtg cttgtgctcc 1921 ctagaaaaac cagcaggtgg tagcaacact tcgtggcaag gccccagccc agctctgtag 1981 gacccaaaca atagacccca aatccccgtc ctcggctaga gaaggggtta gaggtgggcg 2041 gaaacacttt tcctcgcggc gccccctcgg ttcctcaacc ctgcctccag gcgccagctg 2101 agagcacctt gcaccgcccc tcctcactgc agggaggttc tctccggagc gcgggcgagg 2161 gaggaggcac ccagaggtgc agcgacttgc ccaagccatg tcagagccag gcgtacagca 2221 gcgcttcccc ttttcaaccc gactgccctg ccccttgggg agggtagatg gagggaggtt 2281 cgactcagaa gccccaacgt tgaccaagat ccagacacga aaagagaaaa gagttcccgg 2341 ctagcacggc gacgctttca taccgagacg cccccctctc ccgctgcctc ggctccccct 2401 accaccgccc gtactctccc agatttctca gtttgtcttt ccctccaccc cctgcttttc 2461 cttccttctc tcttgctcag ctcacgccca ccttagttca aagctgagta ggagccccac 2521 tgttttagtt cctagagtta aagccgaaga ggagggaggc gcgagggggt gtgtgcaggg 2581 ctctgccctg ccctgaactg ccacggtccg ccagttgcgc ttcgctccgc gggtgtccga 2641 cccaagccga gcccgagccc gagcccaggc aggagcttta cagacagcct cttcccttcc 2701 cacttcctgc aggcgcccca cgcgtgcgat cctcccggcc aagacccgcg ggaggaggcc 2761 gcccccttcc cggcgcacag gcggggcccc gggcgcgccc cgcgtctccc ccgcgcgccg 2821 gggcggagga gcgggcgccg cgcactcacc gcctaggccg ggagggcggg ctcggctccc 2881 cggaagaagg gagtgggaag gcggccaaag gggctgaagg ggcgggccgg gccggcttgg 2941 gaggggacgc ggagggggcg ggccgggctg cgttcgctcc agccgcggct ctacagcagc 3001 gggcggcggg acccgggacc cagcttggcg acggcgatct cgacgcgggc ccccaggatc 3061 tcccggcgcc ccacctctgg agcagcccct gccgccagcg tcaggtccac cccggaatcc 3121 cagggactct cggcgccgaa cggacccggg ccgggtgcaa cggggtcccc ggactggaga 3181 agacgcgggt ggcaccgtgc gagctccagg agccccgggt ccactgcgag gcctcggggg 3241 gcgcagacct gcagagactg cggccaacgg gaaggtgagc ccgcggggtt agcaggcggc 3301 gttgtggggg tcggggacag tatgcttggg gacagaggaa ttaaggtttg caagagtagt 3361 ggggctcccc agcccctagg tggcttcctg agggagtact gaggatcctt cctcaaggcc 3421 agagtggggt tcatgaaggg tgaggaaacg gtcaacctgg ctactcccct ctcactccac 3481 tctgacctgg catcattgac accgcattac ccttgctgtt aggatccccc agttgcgttc 3541 ccagacattc tcctctggct ctggcttggg agtcctaatc tgggagggtc ctcgcagaga 3601 cggagctcca cgcttggaac aggattgcca cccctctgac tccagtggca tcactccaat 3661 ccccttggag ctgggaggag tcaggaggct gaccacacac ctgtcccctg ctccccacaa 3721 ggcactgtcc cccccagctc catgaccaca gttaagcctt ggaggtggaa ggaacgcttg 3781 gttcctgctg cccagccatc acccccaacg tgcaaccaaa ttctattgcg tgctcctgcc 3841 ccagctccac cctcgctctg ctccctccat ctgggtgctt ggccctgctt gccccacacc 3901 cccacccacc gatcttggcc gtctggcacc ctctctcctc ccatccctgg gggagctggc 3961 atggacccag catagcaatg ttgtaatgtc cctggcagcg cccatggagc ggagctgctg 4021 ggtctgttcc cagttaaccc aggccctccg cccgccaggg gaacttgact gaggctctag 4081 gaggggagat gctggtcctg agctgagaga ccagtgggag ggagctgtgt ggggctgtta 4141 gtagaccaca gaagctgccc aagtaagggg cattggagca ttgaggcttc tgagtgctgc 4201 tcagtggggc cacttggctt ttcagagcag tgggcctttt ttctcaaagg aagattagcg 4261 tgggggtgtc tatgtactta cctggtggcc tcagaaggag gacttgtttg gagtctatta 4321 ctccattcag ggtgcaaaaa gatggttggc aatgacactg agttaccaga atgctgggga 4381 gcaacaggct ggggtgggct gagcgtggga aaggcaggat cctccttctg ggacggctgt 4441 tctgctatca ctctgtcctg agcctgggcc ctagaccctg agttcccact ctaggtagaa 4501 ggaggatggc aggttctgga gggtttggga agcctcaggt ttccctttct ttacccactc 4561 ctccccgccc cccacttggc tccctctccc agcccaggtg tttctgcaga agtacctcct 4621 ggggccaaga gcaactcaca gccagactgg gggtagagca ggggccgaag gtgaggaaga 4681 agggcccatg gaaccactcc ggaaccagca ctgatgtgca tcttctgcca caggaaagca 4741 acagccccca tctacacaga cagcatctgc tcccgcccac ctcatctcat acacattccc 4801 ttacacactc caccaggtag acacacatcc tcaggcactg ctgacgcagg tgctactcct 4861 ggcactcagg ggctttcttc cacaaccttc cacttactca tctctcaggc acatttgcct 4921 cctgccttaa caccctccct tatgctcttt tccagagcca cgcatgtccc ccgtcagtgc 4981 acagagtggc tcattctaag tggctgtctg gctagaccta gacactgcct gcatcttaaa 5041 agcctccccc agctccacag cctgggagtg ggaggcacat ttgtctgagt cacagtgctc 5101 tgggggacat tctcaggggc tggaggcctc cagggacaca ggactgtcct ctgctaggta 5161 atctacaaat tggcttctcc agccaaggaa gcagggacta gaagagccgg aggacagcca 5221 cctcctcact gtctgtcctg gatgcctcca tgaagcctga tgatgggatc cttctcaagg 5281 caggaggcca gagcacgaag agatctccaa ggtggagatt aaaggataga ggctttggca 5341 ttaaactgag caaggattat actggaattt cctgggcatt taacagctgt ggaacaggat 5401 aggggacagg gcctgtggta ctgacccctc ccacactgac ctgtgtggct cacaggtgta 5461 aggaccagcc cagcaaccac accagacata aaacctcgaa ccgctttgcc cttgggactg 5521 ttctgtccct gctggactct gcagcctgct ttgtctcact aaattgttcc tgtctgggct 5581 cggtttgggg ccatgccctt tactatgtgt tcccagtgga cagtcccctg ggttcccctc 5641 tgtcccttca tagcctcatc cctttgcttg acatcgtcga agagaagcat gcatgatgtc 5701 agcagcggga cagttggaac ttcttgggag acaagcttaa agactagcca gagataacaa 5761 ttattttggt tttcttgttg gcattacttc actcattcat tctcagctcc tactgtattt 5821 ccacctctac cttcttctta tagatgaaca tttcttgata ttttgaaaca tagaaggaaa 5881 atggcatggg gagtgaataa aatgtaaacg tatgcttatt tgtctaggtt ttacaaatat 5941 ttttcttttt tgtttagatt ttaattatga gattttacgt taattataaa aataaggtat 6001 gcttactgta acaagaaaaa taattgaatt atgtgtaaga caaaattaat gcccccacct 6061 acaatccttc atttctacct cccacagtaa cccattttaa tggcctaata tgtcttctgc 6121 ctaccttcct ccaagcttat ttggcttaca ttatttaatc tttaaaaatt cactttgtgg 6181 attgaggtgc ataaactata ttaagtaagc ttgatttgct catgaaaata tcatatttag 6241 catttaattg gagcacgatt aattttttaa attcttacca atttaccaat ttaatttact 6301 tttaagtcat tctttttttt tttttttttt tttttttttt gagacagcat cttgctctgt 6361 cgccgaggct ggagtgcagt ggcacgatct cggctcactg caagctctgc ctcccgggtt 6421 cacgccattc tcctgcctca gcctccccag cagctgggac tacaggcaca cgccaccacg 6481 cccagctaat tttttttttt tttttttttg tatttttagt agaaacgggg tttcaccgtg 6541 ttagccagga cggtctcgat ctcctgatct tgtgatccgc ccaccttggc ctcccaaagt 6601 gaaatatttc atttttatag caacataact cgtaagctat gctttgtaac ctatgattct 6661 acaaatcttt actttttgcc agtttctgaa aacaaaacac aaccttgata cctaagaaac 6721 agtcttattt ttgtaaacca aagagatgta gcaggcttgt ggatctattg tctctactgt 6781 atcaaaaaga tattaagtga tatatctata aaagaagctg agaacatatt ataaagtcat 6841 agactgcaat ttttgttacc taaaactttg tctaatccgt ctcgttttct ccaccattgt 6901 tttatgttca catttctgct gcttctggtt ttatattttt aaaaccttat acacatctga 6961 aatgtgaata tttttctaaa ggagataagt tcttttgcac attcttgtgt tagagaattt 7021 ctaaatactg accagttcct tttgtaagtc agaggagaga ggactctcaa gcaggctgtg 7081 agagaggagc aaggggcctg gctttgcaga ggctgcttcc catctctgtg gcaggagaaa 7141 tgtactggcc tgtccctggg atgctctcct ggaccaaatg cagaagatgc tccatgccca 7201 caaccattga agacaccttt gaaaaatcaa gttctgagtc ctgcttactt agcattccag 7261 gcatgtggag cagccgtgtt cttgtcactt atgtttctgc ctttgaaatt ggcttcaaaa 7321 gaatctgcag tggtatgaat ttgctgacag caatttattc catatcttaa taaagcttcc 7381 tttttcttta tttggattcc tgcaacaggg gtacacccat attcttttta tatattaaaa 7441 ttaaaagtct tgaatttatc tggtttgttt gataagtaag aactcaccta acttcctagt 7501 ctgactcagc aacaattttt tttttctgaa aaaatgtatt tataaccttc agtcatctgg 7561 atctgaatct aaaagaggtc ctcatcaaac attagaagta tccttctggg tactttaaga 7621 tcctcaacca tttcttttta atgaatatct ttgttcttag taaaatttca aaaaattgct 7681 gaagtggtca tccacaggca gtgtctccat tttcttcttt tctttatgct gtttcttgat 7741 ggcagaagct gagtggcctt aacatccatg tttcataatt gcttttgctc ttttctggat 7801 cttctggagg gaggccagct tcgtgttgtc attacgaggc atgctaaggc tatgcaagca 7861 cgccctattg caaccacaag tgactgtgtt ccttgtagtt cgggtcatca aagcaaatat 7921 cttgctattc atcttccaga gtgttccata ttggacagct gatactatct gcagcgcatc 7981 ttttctatct tgcttggctg tctttcaaaa taattcattg aaatatttcc aaaatattta 8041 ttgttccttc ttcatgatta tttgcctagt tgtaagcttg agaagacaca gggcttactg 8101 tttcttcttt gtacagatta cagaatccat ccatgttctg agtgaaagaa agagactatt 8161 ttaaagaata acttctaggc aaatggtaaa atagccttca ttgtttaaaa acctgctgct 8221 ggcattttct ttccctgata acagtatttc taaggactcc gtgactctgg tttgcttcag 8281 tgtgtcaagc acgtctccaa attaagccat tgagagtttg gaggggatgc acttacaaca 8341 tgaattactt taggatattt attaaacagc cactggtgac ggtgccaagg ttacagaatt 8401 taatagctat gcctgctttt tacttcatga tctccccgtt cctctccaaa gcatttattt 8461 catctgtgaa ggatcctagt aacatttcag acatttttgc aaagaacatt acttaagagc 8521 aatttgccat atggaaatgc tccttacttg tctccatagg ctgtaaattg aactctctat 8581 ttcacaaata gggttaaaga tgtataaaag gtgagtttca ggggctagtt ggcaggtgcc 8641 cactctacat cagcccacgc gtatgtagaa atggtgtatt tccatgataa cttcatggac 8701 agcacagccc gcagtgccag aaaaaaatta gtaggaatca aattatgatt ttcatatttg 8761 ttgcaattaa agtttcatag tttgattttt gttttatgat agctttcaac aatcccaagg 8821 ccatatatat ccaggaaaaa caaatcacaa cttctcttct aattggcttt ttttttgttt 8881 tcctctcagt tctatgtctt ttgagcaatc tgggcaacat gtctcttttt tttcttcaca 8941 gaaataaagg gattatagtc cacccaattc acagacttct gagactcaga cacgaggaga 9001 gatagagaac cgccaatctc tagatcaaca agcaaaggag gtgccaagcc tgtttgtctt 9061 cattgtgaca ctggaggtag ctattccttc tgttcatttg ctcgtgagct tagtggtgta 9121 ccttctgaag gcacaggaag gttttatata agaggtagct tactacatag ttctgagaag 9181 ccattatgag gatatgaaca ctgttttgat taactttact aaacagttat tatcctatag 9241 ttttaaagaa aattttaatc aatgatttag ttgaaagaat acacatgcaa gagtttaaga 9301 atgcaaaaat ttaaatggat acaattaatg agaatacaat gaaagttaag tctcccttgc 9361 actgggtctc agtccacttc ctttgccttt ttcacaggtt ttggatgctc ttccatagat 9421 atccttccat acatatgtat gtgtatatat ccttcttaac aaaggggagc ttactttaca 9481 ctgttctcca ttgtcccact ttcacttgga aatgcttttt atatcagtgc atcaacagtt 9541 gcccgtattt ctttctaagg atgtactata attttactgt cttccaattg atggacagtt 9601 agtttacagc cttttctctt ataaacaatt tgcaattaat gtctttgttc aaacatctgt 9661 gcaaacccat acaagtatac agtacctgaa ggacacattc ttacaatgta gttgctggaa 9721 agatattacc caattgtcct cccaagagaa tattccaatt tggattcaag cagagtatgt 9781 acaagagaac ctatttccca tatcttgtcc aacatggtaa aaatggtgtc ttaggcaact 9841 gtggctgcca taacaaagtg caatagacct agtagcttat acacaataga aatatctttc 9901 tcacagtcta gatgctggga agtccaagat cagggtgccg gcatggtcag ttcctggcga 9961 agcctctctt ctaggtttca gactgccctc ttctttgttg tgtcctcgaa tggcagaaaa 10021 agggtgagaa agccctttgg ggtctctttc atctgggcac taatctcatg attagtgagg 10081 gctccaccct catgacctaa aatttcctcc caaaggcccc atcttctaat accatcatct 10141 tgggagttag gatttcaaca tatgaatgga gggggggcac aaatattcct tctataacaa 10201 atggcctgtt gctgtagttt taacctggtt tcctttcaat gtgagcaaac aagaagcatc 10261 ttttcatatg ttaaagccat agggttattc ttctgtaagc tctaggaaaa catgcacccc 10321 ttggggcacg aggatctttg ttcacaaagt gtatgccaga cctccatagc tctgccccct 10381 ccctgcactg tctcatttat cagactgaat cttcatgcct gtgttctttc tgtatttatt 10441 ctggtccctt ccctcccatc ataccccaca gccatcttcc tgtgtccctc ccgcttcact 10501 gcttcactgc ccctctgaaa tttctagagc atccaggtcc atcgggggtg gggcggtgtg 10561 gtgaggattc aattcatgtg tctgtaggat gcagcagctt cttaaccagc tgcctttaat 10621 gaaaatcttc taacttccaa tacagggtgg ctgttggagg aagggaggag agtaaatgaa 10681 gagaaagaac tggaataacc ccttgcagaa aaaaaaaaaa agggtaagat tgacccagaa 10741 acaccctctg ccccacttct aggaaggaga gctgtgagaa atgaacacag agacagggtc 10801 acacagggag taggcacgaa cactccaaga tggtcaaatg tgcaccggct caggagaggc 10861 agtatgcaac ctggcttctg tcccatggtg ggtgctgggg cgattggaga gctgtaggag 10921 gagacacaga cacggggtca gcttttggag cttgggctgt atatgaagaa acactttctt 10981 cccacctgcc tcttctggtc ttgtgtgtct cctcaggaag caagcttagc tgtacaccct 11041 gagtcttgca aaagctgcag ccccacccag gagcagggtg gtggctgggg cgatggtgga 11101 cgccctgaag atgtcccatg gctactgaag gggctgccca gttagggaac agagtggcgg 11161 gcatggtgtg tagcctatgg gtgctgctcc tggtgtcttc agttctggct ctggaaggta 11221 agagggaggg gagacaggag aacccagacc tgccatagag acccagtgaa agggggaagt 11281 gggaaagatt tagaaaaggt agataagagt gaagacatca ataaagggaa aggcatggtg 11341 aggataatga agacccacat cagatttgtc agagaaagga ccctgacgga cagctgtgct 11401 cctgctggca aagacatggg cccgggtggg gcattctttt gttcccggtg ggaatagagt 11461 aggggctggc agtgctggct ggaggcttgg ccactgtgtg cccctcttat ttctgggcag 11521 aggtattgct ggacaccacc ggagagacat ctgagattgg ctggctcacc tacccaccag 11581 ggggggtgag tgccactcta attctgaacc tgaatccctt ggccctgccc ctccctgttc 11641 cctggagagt ggaattcatg aaggaaaccc tgggtgagga ttatgggaaa aggatccctc 11701 cctctagagc accaagattt caaggtatcc tctatctgct ttgcttgtca ttaattttaa 11761 gtctcagtgg aagagatatg tccccttccc tataacctct acctcgcctt gcttaagccc 11821 ggagccccta aagcttctcc tggcccttcc tgcagtggga cgaggtgagt gttctggacg 11881 accagcgacg cctgactcgg acctttgagg catgtcatgt ggcaggggcc cctccaggca 11941 ccgggcagga caattggttg cagacacact ttgtggagcg gcgcggggcc cagagggcgc 12001 acattcgact ccacttctct gtgcgggcat gctccagcct gggtgtgagc ggcggcacct 12061 gccgggagac cttcaccctt tactaccgtc aggctgagga gcccgacagc cctgacagcg 12121 tttcctcctg gcacctcaaa cgctggacca aggtggacac aattgcagca gacgagagct 12181 ttccctcctc ctcctcctcc tcctcctctt cttcctctgc agcgtgggct gtgggacccc 12241 acggggctgg gcagcgggct ggactgcaac tgaacgtcaa agagcggagc tttgggcctc 12301 tcacccaacg cggcttctac gtggccttcc aggacacggg ggcctgcctg gccctggtcg 12361 ctgtcaggct cttctcctac acctgccctg ccgtgctccg atcctttgct tcctttccag 12421 agacgcaggc cagtggggct gggggggcct ccctggtggc agctgtgggc acctgtgtgg 12481 ctcatgcaga gccagaggag gatggagtag ggggccaggc aggaggcagc ccccccaggc 12541 tgcactgcaa cggggagggc aagtggatgg tagctgtcgg gggctgccgc tgccagcctg 12601 gataccaacc agcacgagga gacaaggcct gccaaggtga gagcccactc gtcttgcact 12661 tgcccgacac ctcccaccca cccccagcct ttgggctcct ctctgaacac cccaaaattc 12721 attttatctg caaaaggtca ggaataagcc atcttaggaa aggaccctga ttttccctaa 12781 ttttatttct taaagcactc aaacttacta tcacccactc atctgaaatt tctggaatct 12841 tctggagcct ttcacagcaa ttgccttttc ctaagtcttc aggcctgaga agcgatggag 12901 accaaaagga gtttagctcc agctccaggg ttactatgga atagagtcct ttggttccca 12961 ttcgcccttc tgttgggagg gtccctgcct cgctgggcca ggtgacaggg acgcaggtag 13021 aggaaggcag tggatggcag ctagggagaa tgactgcagc agcaggcctc cgcagaggga 13081 gcttatgcaa taagctggga acacccacat ctggcactgg gcctgtctgt aacccccact 13141 gcacctcact ttctccatcc atggaaatgc aattctgtcc cagcaattgg cagaagaaat 13201 ctctgcctga gggaagagag ggtggggttc agtcttggaa gaaaaggaga accagctctg 13261 gggaagagaa ggctgcgagg atacctgcct gctgtgtgtt gggagctcag ggtgggtgga 13321 cagagcgagt gtgacgcccc cactctcctc tgcctcctca gcctgcccac gggggctcta 13381 taagtcttct gctgggaatg ctccctgctc accatgccct gcccgcagtc acgctcccaa 13441 cccagcagcc cccgtttgcc cctgcctgga gggcttctac cgggccagtt ccgacccacc 13501 agaggccccc tgcactggtg agttcctcac ccagccctgc aatgggaaag agacttggag 13561 aggggccaga agtgggggta gcaggcaaca ctgggggctc tttgcatttg gagtgacttg 13621 tttttcccct attttcttgg cttcctcccc tccctgtccc cacccccttc tctccctgac 13681 ccatccttcc ctgggcccac atcctgcctc tctgggctac ccccacccca cgctcttctg 13741 tctccttccc tctcggccac ccaccctccc ctggctcctt ccttcctcaa tcacccccac 13801 tgctgccctc ttggcccttg gactgccata tcctccggcc ccccaggtcc tccatcggct 13861 ccccaggagc tttggtttga ggtgcaaggc tcagcactca tgctacactg gcgcctgcct 13921 cgggagctgg ggggtcgagg ggacctgctc ttcaatgtcg tgtgcaagga gtgtgaaggc 13981 cgccaggaac ctgccagcgg tggtgggggc acttgtcacc gctgcaggga tgaggtccac 14041 ttcgaccctc gccagagagg cctgactgag agccgagtgt tagtgggggg actccgggca 14101 cacgtaccct acatcttaga ggtgcaggct gttaatgggg tgtctgagct cagccctgac 14161 cctcctcagg ctgcagccat caatgtcagc accagccatg aaggtgagct cttttccttg 14221 gccttcagga tcccctgcct ccgctccttt gagccccctt ccctactcct gatctccagc 14281 ctggtccacc cctgccgccc tcccctcaag gctgatcctg ctcccaggga ctcctatccc 14341 cataataatt ttccttttgc actctagtgc cctctgctgt ccctgtggtg caccaggtga 14401 gccgggcatc caacagcatc acggtgtcct ggccgcagcc cgaccagacc aatgggaaca 14461 tcctggacta tcagctccgc tactatgacc aggtgcgcag gaggagtggg ggttccgcag 14521 tagggctggt aggagctcat aggcctcaca gtggggccca gaggtgacca ggtgcacagg 14581 aggaatgagg ggtccgcaac agggctggca ggagctcaca gtccccacag taggggccag 14641 aggctgaatg ggcaaggaga ggtgcccaga agtgtgcagc actgggcatg tgtctgagag 14701 ccctgtcaac cagggagggt ggctgggggc cttaggggca gaagcagggg caagaggggg 14761 ccaggcaggg agtgagtggc tgttaccccc aggcagaaga cgaatcccac tccttcaccc 14821 tgaccagcga gaccaacact gccaccgtga cacagctgag ccctggccac atctatggtt 14881 tccaggtgcg ggcccggact gctgccggcc acggccccta cgggggcaaa gtctatttcc 14941 agacacttcc tcaaggtgag cgggggtcaa gggccagatg ggcaggtgaa ggcccaagtg 15001 ggtagtgagg agaggcccag ggactgtccg gccttgaacc ctggccccgt gcttcccaac 15061 cagaagttct gtgggaaagg agagtgcctt ttgctcagca gctgacctag gggctactcg 15121 gggaggtggg gaattgtagg ggtatgtatg catgttgagt gtggatatag gagggctgtg 15181 gggatgtgtg tgtgtgttgt gtgtccctgg gtgtggatgt gggagggctg tgggcgtgtg 15241 tgtgtgttgt gtgtccctgt gtgtggatgt ggagggctgt ggggatgtgt gtgtgtgttg 15301 tgtgtccctg tgtgtggatg tgggagggct gtgggcgtgt gtgtgtgttg tgtgtccctg 15361 tgcatggatg tgggaggttt ggggcatgcg cgtgcatgtt gtgtgtgcct gtggtgtgtg 15421 tgggtgcctg ggcacatgaa caagcacctg tgagagacct ggcccacctg tgaccctgtc 15481 ggctggtccc ccaggggagc tgtcttccca gcttccggaa agactctcct tggtgatcgg 15541 ctccatcctg ggggctttgg ccttcctcct gctggcagcc atcaccgtgc tggcggtcgt 15601 cttccagcgg tgagtcccca cccctgccca actctgccca gcaccattaa ctccacagcc 15661 aaacctcaag tcctgccaag tctggagccc cctgcagaaa cctcacactg gtgctcctcc 15721 cgtcagccag cccctgccct gggccccacg tggagatggg caggagggcc aggctgtcgt 15781 cccccctcca cagaccgact aaagagcagt ctggagggtg acaagggggc agcaaggggg 15841 tggaaatggg agcgtcatcc ccagtcaccg ttttgttcct caggaagcgg cgtgggactg 15901 gctacacgga gcagctgcag caatacagca gcccaggtgg ggatgaggag aggaaatggg 15961 tggggctggg gaacacatgg gtggggcaca tggcaggcaa ggctggatcc ccccaagatt 16021 gggggagctc cttggcacaa ccttctggag gtaagtgggc atgtctgggg tgcgcgggca 16081 gccctgcctt tcacaacacg ctcataacat actccacacc cctccaggac tcggggtgaa 16141 gtattacatc gacccctcca cctacgagga cccctgtcag gccatccgag aacttgcccg 16201 ggaagtcgat cctgcttata tcaagattga ggaggtcatt gggacaggta cagcagggcc 16261 aaagcaggga tcagagcgac ggggctccct tgtggcctcc gctggccaga gtcccatcca 16321 aacacagcag gacgctgtga gccttgatcc ccaccccaac ctacacctat tttcccaggc 16381 tcttttggag aagtgcgcca gggccgcctg cagccacggg gacggaggga gcagactgtg 16441 gccatccagg ccctgtgggc cgggggcgcc gaaagcctgc agatgacctt cctgggccgg 16501 gccgcagtgc tgggtcagtt ccagcacccc aacatcctgc ggctggaggg cgtggtcacc 16561 aagagccgac ccctcatggt gctgacggag ttcatggagc ttggccccct ggacagcttc 16621 ctcagggtca gtccagcctg ggtgaaggag gagggtcctt gggtccagga aagcttccag 16681 gagacgaggt cctgtatctt tgcttcttac caccccacct tccatggtct ccgtccttcc 16741 ttcccagcca ttttctgatt cgacaccctc cccctctcat gctgttgtct gctgtgcagt 16801 atgttgaggt ctccccctgt ctccgatcac tgacctctgc cccctgcccc ttcccctcag 16861 cagcgggagg gccagttcag cagcctgcag ctggtggcca tgcagcgggg agtggctgct 16921 gccatgcagt acctgtccag ctttgccttc gtccatcgct cgctgtctgc ccacagcgtg 16981 ctggtgaata gccacttggt gtgcaaggtg gcccgtcttg gccacagtcc tcaggtgaga 17041 gcacagcctt ggggacacag cctggggcct tgtggcatgc cccagcaggt gctggggtcg 17101 ggggtgagct ggaatctggg gtaggtacct cagccggggt gtcatagtcc ctgaaaggag 17161 ggaggctctc ctgtgtgatg gggagatgaa agcctaggcg acggggtttg agggatttca 17221 gggaccgaga caaaggggat gagggagggg aggagacctg caacaatcta gaactacctc 17281 ctgcccttcc cccattgtgg agattacaca gactccagag tcagcacagc tgggtacaaa 17341 ttcttaacac tctgctctcc agctctgtga ccttggacaa gttcactttc tctaagcttc 17401 accttctgct tctgtgaaat ggagataata tcatccacct tggagggttg ttatgaggat 17461 taaatgagat gcttgatgta aaacccttaa catatctgag cacatagtag ttgctccata 17521 aacgtgacta ttgcttctgc ttctgtgaaa tggagatgat atcatccacc ttagagggtt 17581 gttatgagga ttaaatgaga tgcttgatgt aaaacccttg gcatatctga gcacatagta 17641 gttgctcaat aaacgtgact attactatga ttattactat ttgcttttga ctttacccct 17701 cagggcccaa gttgtttgct tcgctgggca gccccagagg tcattgcaca tggaaagcat 17761 acaacatcca gtgatgtctg gagctttggg atactcatgt gggaagtgat gagttatgga 17821 gaacggcctt actgggacat gagtgagcag gaggtgagca ctgacctaga cactgctgat 17881 ttcccacccc gatccctccc aggttggaac attctaggac ctccattctc tactccgttt 17941 gtattctaag atctcatggc tgttggattg ccatatcttt gagttccttc tccactccaa 18001 cctcatgctc caccagattc cagcccaccc tcttacccaa caaagtactc ccctctacta 18061 acaaaacttc ccatcatcat agtcttcctc tgacccccag gtactaaatg caatagagca 18121 ggagttccgg ctgcccccgc ctccaggctg tcctcctgga ttacatctac ttatgttgga 18181 cacttggcag aaggaccgtg cccggcggcc tcattttgac cagctggtgg ctgcatttga 18241 caagatgatc cgcaagccag ataccctgca ggctggcggg gacccagggg aaaggtctgg 18301 agcttggggc tagagcctgg gaaagccagg gagggtagat gcaaacctaa agaaaactga 18361 ggagaggggc taagatgaag aggagacctt gaccctgctt gcccctcccc tcttaggcct 18421 tcccaggccc ttctgacccc tgtggccctg gactttcctt gtctggactc accccaggcc 18481 tggctttcag ccattggact ggagtgctac caggacaact tctccaagtt tggcctctgt 18541 accttcagtg atgtggctca gctcagccta gagtaagcag ggagtggtgg ggtgggggcg 18601 aatgctccag gcccctggct gggggtcgta ttggggatct cggagaagct ggcccagatt 18661 tgatcccttc cctccccacc agagacctgc ctgccctggg catcaccctg gctggccacc 18721 agaagaagct gctgcaccac atccagctcc ttcagcaaca cctgaggcag cagggctcag 18781 tggaggtctg agaatgacga tacccgtgac tcagccctgg acactggtcc gagaagggac 18841 atgtgggacg tgagccgggc tccaacagcc tctgtgagag atgccccaca ccaaacccaa 18901 ccctcccgat ggctgcattc cctggtcctc cgcctctcca ccagccccct cctcattaaa 18961 gggaaagaag ggaatttgca agtttggtgt ggtgaggcct cagtctgcaa caaagggtga 19021 gggaggcctc aacgtaggag cagaggggtg gggccggcag atggcactgc agagatgcag 19081 aagggcagct gggcagggat ccgaaaacga ctttattgaa gatggagttg gcaagaccta 19141 gccccacttc ccacccccag agccgttcct gtctccctca ctcacacgct ttccacaagc 19201 tctgcacttc cctgcacctg cctgggtgcc ctgggaaggg ctctctcccc acttatgacc 19261 ctggggtgga gaccgagcgc ccaagcaggc tggcctgttt ttaaagtgct ctgacatgca 19321 gtgctcctgt cggaagggtg atgagcaggc cacaggagag ttcctcacgc cctgccagcc 19381 ccgtgcttgg gctgggcttc ctctgcccca gagctgaagg agtaatgcag gcctggagca 19441 gtgattctca acgtacattc cttggcgttc atgctactcc tctttctccc ctggggcctg 19501 ggagatgaga cctctgggtg tttggttttt gttttgtttg atgcacccag gaaaatgaga 19561 gcaagttcca ggaagcgaag tgagaacacg cagtcagatc tgatattccc agctctcccc 19621 gtcctccaga cccctgttga ttatcccacg caggt //