LOCUS ACTB 7399 bp DNA linear PRI 25-MAR-2004 DEFINITION Homo sapiens ACTB: actin, beta (ACTB) gene, complete cds. ACCESSION ACTB VERSION KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 7399) AUTHORS Livingston,R.J., Rieder,M.J., Chung,M.-W., Ritchie,T.K., Olson,A.N., Nguyen,C.P., Nguyen,D.A., Poel,C.L., Robertson,P.D., Schackwitz,W.S., Sherwood,J.K., Sherwood,A.M., Leithauser,B.J. and Nickerson,D.A. TITLE Direct Submission JOURNAL Submitted (25-MAR-2004) Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195, USA COMMENT To cite this work please use: NIEHS-SNPs, Environmental Genome Project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu). FEATURES Location/Qualifiers source 1..7399 /organism="Homo sapiens" /db_xref="taxon:9606" variation 28 /frequency="0.19" /replace="T" variation 174..179 /frequency="0.62" /replace="" variation 304 /frequency="0.01" /replace="A" variation 307 /frequency="0.01" /replace="C" variation 541 /frequency="0.39" /replace="A" variation 768 /frequency="0.01" /replace="A" variation 1036 /frequency="0.01" /replace="T" variation 1078 /frequency="0.38" /replace="G" variation 1378 /frequency="0.02" /replace="T" variation 1383 /frequency="0.01" /replace="T" variation 1488 /frequency="0.01" /replace="T" gene 1945..5380 /gene="ACTB" mRNA join(1945..2011,2872..3000,3135..3374,3816..4254, 4350..4531,4644..5380) /gene="ACTB" /product="ACTB" variation 1945 /gene="ACTB" /frequency="0.01" /replace="T" variation 2038 /gene="ACTB" /frequency="0.23" /replace="T" variation 2044..2065 /gene="ACTB" /frequency="0.34" /replace="" variation 2127 /gene="ACTB" /frequency="0.01" /replace="" variation 2219 /gene="ACTB" /frequency="0.11" /replace="T" variation 2323 /gene="ACTB" /frequency="0.23" /replace="T" variation 2335 /gene="ACTB" /frequency="0.01" /replace="A" variation 2339 /gene="ACTB" /frequency="0.10" /replace="T" variation 2451 /gene="ACTB" /frequency="0.34" /replace="T" variation 2563 /gene="ACTB" /frequency="0.01" /replace="T" variation 2839 /gene="ACTB" /frequency="0.32" /replace="T" variation 2868 /gene="ACTB" /frequency="0.01" /replace="T" CDS join(2878..3000,3135..3374,3816..4254,4350..4531, 4644..4787) /gene="ACTB" /codon_start=1 /product="ACTB: actin, beta" /translation="MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVM VGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHP VLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVT HTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCY VALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHE TTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPE RKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF" variation 3077 /gene="ACTB" /frequency="0.01" /replace="G" variation 3119 /gene="ACTB" /frequency="0.01" /replace="A" variation 3131 /gene="ACTB" /frequency="0.01" /replace="T" variation 3179 /gene="ACTB" /frequency="0.01" /replace="T" variation 3404 /gene="ACTB" /frequency="0.01" /replace="G" variation 3501 /gene="ACTB" /frequency="0.02" /replace="A" variation 3647 /gene="ACTB" /frequency="0.01" /replace="T" variation 3696 /gene="ACTB" /frequency="0.01" /replace="A" variation 3772 /gene="ACTB" /frequency="0.01" /replace="T" variation 3778 /gene="ACTB" /frequency="0.01" /replace="T" variation 3800 /gene="ACTB" /frequency="0.49" /replace="C" variation 3872 /gene="ACTB" /frequency="0.01" /replace="G" variation 4447 /gene="ACTB" /frequency="0.01" /replace="C" variation 4450 /gene="ACTB" /frequency="0.01" /replace="T" variation 4489 /gene="ACTB" /frequency="0.04" /replace="A" variation 4498 /gene="ACTB" /frequency="0.01" /replace="T" variation 4570 /gene="ACTB" /frequency="0.35" /replace="A" variation 4703 /gene="ACTB" /frequency="0.01" /replace="A" variation 4887 /gene="ACTB" /frequency="0.01" /replace="C" variation 4997 /gene="ACTB" /frequency="0.01" /replace="T" variation 5054 /gene="ACTB" /frequency="0.37" /replace="A" variation 5240 /gene="ACTB" /frequency="0.03" /replace="G" variation 5292 /gene="ACTB" /frequency="0.01" /replace="A" variation 5495 /frequency="0.35" /replace="C" variation 5571 /frequency="0.05" /replace="" variation 5615 /frequency="0.03" /replace="" variation 5620 /frequency="0.02" /replace="G" variation 5785 /frequency="0.01" /replace="T" variation 5813 /frequency="0.36" /replace="A" variation 5820 /frequency="0.01" /replace="" variation 5864 /frequency="0.04" /replace="G" variation 5945 /frequency="0.01" /replace="A" variation 5972 /frequency="0.42" /replace="G" variation 5988 /frequency="0.01" /replace="T" variation 6049 /frequency="0.01" /replace="G" variation 6113 /frequency="0.01" /replace="C" variation 6152 /frequency="0.01" /replace="A" repeat_region 6167..6330 /rpt_family="Alu" /rpt_type=dispersed variation 6242 /frequency="0.01" /replace="T" variation 6244 /frequency="0.07" /replace="T" variation 6291 /frequency="0.02" /replace="T" variation 6308 /frequency="0.09" /replace="A" variation 6466 /frequency="0.01" /replace="A" variation 6561 /frequency="0.01" /replace="A" repeat_region 6708..6819 /rpt_family="L2" /rpt_type=dispersed variation 6732 /frequency="0.06" /replace="C" variation 6741 /frequency="0.01" /replace="T" variation 6846 /frequency="0.01" /replace="C" variation 6860..6863 /frequency="0.02" /replace="" variation 6862 /frequency="0.01" /replace="C" variation 6900 /frequency="0.01" /replace="C" repeat_region 6917..7146 /rpt_family="L2" /rpt_type=dispersed variation 6922..6941 /frequency="0.97" /replace="" variation 6962..6965 /frequency="0.99" /replace="" variation 7031 /frequency="0.01" /replace="T" repeat_region 7228..7379 /rpt_family="Alu" /rpt_type=dispersed BASE COUNT 1359 a 2234 c 2195 g 1611 t ORIGIN 1 acctgacaac ctctcatccc tgctctgcag atccggtccc atccccactg cccaccccac 61 ccccccagca ctccacccag ttcaacgttc cacgaacccc cagaaccagc cctcatcaac 121 aggcagcaag aagggccccc cgcccatcgc cccacaacgc cagccgggtg aactgtagcg 181 ttggcaggtc ctgaggcagc tggcaagacg cctgcagctg aaagatacaa ggccagggac 241 aggacagtcc catccccagg aggcagggag tatacaggct ggggaagttt gcccttgcgt 301 ggggtggtga tggaggaggc tcagcaagtc ttctggactg tgaacctgtg tctgccactg 361 tgtgctgggt ggtggtcatc tttcccacca ggctgtggcc tctgcaacct tcaagggagg 421 agcaggtccc attggctgag cacagccttg taccgtgaac tggaacaagc agcctccttc 481 ctggccacag gttccatgtc cttatatgga ctcatctttg cctattgcga cacacactca 541 gtgaacacct actacgcgct gcaaagagcc ccgcaggcct gaggtgcccc cacctcacca 601 ctcttcctat ttttgtgtaa aaatccagct tcttgtcacc acctccaagg agggggagga 661 ggaggaaggc aggttcctct aggctgagcc gaatgcccct ctgtggtccc acgccactga 721 tcgctgcatg cccaccacct gggtacacac agtctgtgat tcccggagca gaacggaccc 781 tgcccacccg gtcttgtgtg ctactcagtg gacagaccca aggcaagaaa gggtgacaag 841 gacagggtct tcccaggctg gctttgagtt cctagcaccg ccccgccccc aatcctctgt 901 ggcacatgga gtcttggtcc ccagagtccc ccagcggcct ccagatggtc tgggagggca 961 gttcagctgt ggctgcgcat agcagacata caacggacgg tgggcccaga cccaggctgt 1021 gtagacccag cccccccgcc ccgcagtgcc taggtcaccc actaacgccc caggccttgt 1081 cttggctggg cgtgactgtt accctcaaaa gcaggcagct ccagggtaaa aggtgccctg 1141 ccctgtagag cccaccttcc ttcccagggc tgcggctggg taggtttgta gccttcatca 1201 cgggccacct ccagccactg gaccgctggc ccctgccctg tcctggggag tgtggtcctg 1261 cgacttctaa gtggccgcaa gccacctgac tcccccaaca ccacactcta cctctcaagc 1321 ccaggtctct ccctagtgac ccacccagca catttagcta gctgagcccc acagccagag 1381 gtcctcaggc cctgctttca gggcagttgc tctgaagtcg gcaaggggga gtgactgcct 1441 ggccactcca tgccctccaa gagctccttc tgcaggagcg tacagaaccc agggccctgg 1501 cacccgtgca gaccctggcc caccccacct gggcgctcag tgcccaagag atgtccacac 1561 ctaggatgtc ccgcggtggg tggggggccc gagagacggg caggccgggg gcaggcctgg 1621 ccatgcgggg ccgaaccggg cactgcccag cgtggggcgc gggggccacg gcgcgcgccc 1681 ccagcccccg ggcccagcac cccaaggcgg ccaacgccaa aactctccct cctcctcttc 1741 ctcaatctcg ctctcgctct tttttttttt cgcaaaagga ggggagaggg ggtaaaaaaa 1801 tgctgcactg tgcggcgaag ccggtgagtg agcggcgcgg ggccaatcag cgtgcgccgt 1861 tccgaaagtt gccttttatg gctcgagcgg ccgcggcggc gccctataaa acccagcggc 1921 gcgacgcgcc accaccgccg agaccgcgtc cgccccgcga gcacagagcc tcgcctttgc 1981 cgatccgccg cccgtccaca cccgccgcca ggtaagcccg gccagccgac cggggcaggc 2041 ggctcacggc ccggccgcag gcggccgcgg ccccttcgcc cgtgcagagc cgccgtctgg 2101 gccgcagcgg ggggcgcatg gggggggaac cggaccgccg tggggggcgc gggagaagcc 2161 cctgggcctc cggagatggg ggacacccca cgccagttcg gaggcgcgag gccgcgctcg 2221 ggaggcgcgc tccgggggtg ccgctctcgg ggcgggggca accggcgggg tctttgtctg 2281 agccgggctc ttgccaatgg ggatcgcagg gtgggcgcgg cggagccccc gccaggcccg 2341 gtgggggctg gggcgccatt gcgcgtgcgc gctggtcctt tgggcgctaa ctgcgtgcgc 2401 gctgggaatt ggcgctaatt gcgcgtgcgc gctgggactc aaggcgctaa ctgcgcgtgc 2461 gttctggggc ccggggtgcc gcggcctggg ctggggcgaa ggcgggctcg gccggaaggg 2521 gtggggtcgc cgcggctccc gggcgcttgc gcgcacttcc tgcccgagcc gctggccgcc 2581 cgagggtgtg gccgctgcgt gcgcgcgcgc cgacccggcg ctgtttgaac cgggcggagg 2641 cggggctggc gcccggttgg gagggggttg gggcctggct tcctgccgcg cgccgcgggg 2701 acgcctccga ccagtgtttg ccttttatgg taataacgcg gccggcccgg cttcctttgt 2761 ccccaatctg ggcgcgcgcc ggcgccccct ggcggcctaa ggactcggcg cgccggaagt 2821 ggccagggcg ggggcgacct cggctcacag cgcgcccggc tattctcgca gctcaccatg 2881 gatgatgata tcgccgcgct cgtcgtcgac aacggctccg gcatgtgcaa ggccggcttc 2941 gcgggcgacg atgccccccg ggccgtcttc ccctccatcg tggggcgccc caggcaccag 3001 gtaggggagc tggctgggtg gggcagcccc gggagcgggc gggaggcaag ggcgctttct 3061 ctgcacagga gcctcccggt ttccggggtg ggggctgcgc ccgtgctcag ggcttcttgt 3121 cctttccttc ccagggcgtg atggtgggca tgggtcagaa ggattcctat gtgggcgacg 3181 aggcccagag caagagaggc atcctcaccc tgaagtaccc catcgagcac ggcatcgtca 3241 ccaactggga cgacatggag aaaatctggc accacacctt ctacaatgag ctgcgtgtgg 3301 ctcccgagga gcaccccgtg ctgctgaccg aggcccccct gaaccccaag gccaaccgcg 3361 agaagatgac ccaggtgagt ggcccgctac ctcttctggt ggccgcctcc ctccttcctg 3421 gcctcccgga gctgcgccct ttctcactgg ttctctcttc tgccgttttc cgtaggactc 3481 tcttctctga cctgagtctc ctttggaact ctgcaggttc tatttgcttt ttcccagatg 3541 agctcttttt ctggtgtttg tctctctgac taggtgtcta agacagtgtt gtgggtgtag 3601 gtactaacac tggctcgtgt gacaaggcca tgaggctggt gtaaagcggc cttggagtgt 3661 gtattaagta ggcgcacagt aggtctgaac agactcccca tcccaagacc ccagcacact 3721 tagccgtgtt ctttgcactt tctgcatgtc ccccgtctgg cctggctgtc cccagtggct 3781 tccccagtgt gacatggtgt atctctgcct tacagatcat gtttgagacc ttcaacaccc 3841 cagccatgta cgttgctatc caggctgtgc tatccctgta cgcctctggc cgtaccactg 3901 gcatcgtgat ggactccggt gacggggtca cccacactgt gcccatctac gaggggtatg 3961 ccctccccca tgccatcctg cgtctggacc tggctggccg ggacctgact gactacctca 4021 tgaagatcct caccgagcgc ggctacagct tcaccaccac ggccgagcgg gaaatcgtgc 4081 gtgacattaa ggagaagctg tgctacgtcg ccctggactt cgagcaagag atggccacgg 4141 ctgcttccag ctcctccctg gagaagagct acgagctgcc tgacggccag gtcatcacca 4201 ttggcaatga gcggttccgc tgccctgagg cactcttcca gccttccttc ctgggtgagt 4261 ggagactgtc tcccggctct gcctgacatg agggttaccc ctcggggctg tgctgtggaa 4321 gctaagtcct gccctcattt ccctctcagg catggagtcc tgtggcatcc acgaaactac 4381 cttcaactcc atcatgaagt gtgacgtgga catccgcaaa gacctgtacg ccaacacagt 4441 gctgtctggc ggcaccacca tgtaccctgg cattgccgac aggatgcaga aggagatcac 4501 tgccctggca cccagcacaa tgaagatcaa ggtgggtgtc tttcctgcct gagctgacct 4561 gggcaggtcg gctgtggggt cctgtggtgt gtggggagct gtcacatcca gggtcctcac 4621 tgcctgtccc cttccctcct cagatcattg ctcctcctga gcgcaagtac tccgtgtgga 4681 tcggcggctc catcctggcc tcgctgtcca ccttccagca gatgtggatc agcaagcagg 4741 agtatgacga gtccggcccc tccatcgtcc accgcaaatg cttctaggcg gactatgact 4801 tagttgcgtt acaccctttc ttgacaaaac ctaacttgcg cagaaaacaa gatgagattg 4861 gcatggcttt atttgttttt tttgttttgt tttggttttt tttttttttt tggcttgact 4921 caggatttaa aaactggaac ggtgaaggtg acagcagtcg gttggagcga gcatccccca 4981 aagttcacaa tgtggccgag gactttgatt gcacattgtt gtttttttaa tagtcattcc 5041 aaatatgaga tgcgttgtta caggaagtcc cttgccatcc taaaagccac cccacttctc 5101 tctaaggaga atggcccagt cctctcccaa gtccacacag gggaggtgat agcattgctt 5161 tcgtgtaaat tatgtaatgc aaaatttttt taatcttcgc cttaatactt ttttattttg 5221 ttttattttg aatgatgagc cttcgtgccc ccccttcccc cttttttgtc ccccaacttg 5281 agatgtatga aggcttttgg tctccctggg agtgggtgga ggcagccagg gcttacctgt 5341 acactgactt gagaccagtt gaataaaagt gcacacctta aaaatgaggc caagtgtgac 5401 tttgtggtgt ggctgggttg ggggcagcag agggtgaacc ctgcaggagg gtgaaccctg 5461 caaaagggtg gggcagtggg ggccaacttg tccttaccca gagtgcaggt gtgtggagat 5521 ccctcctgcc ttgacattga gcagccttag agggtggggg aggctcaggg gtcaggtctc 5581 tgttcctgct tattggggag ttcctggcct ggcccttcta tgtctcccca ggtaccccag 5641 tttttctggg ttcacccaga gtgcagatgc ttgaggaggt gggaagggac tatttggggg 5701 tgtctggctc aggtgccatg cctcactggg gctggttggc acctgcattt cctgggagtg 5761 gggctgtctc agggtagctg ggcacggtgt tcccttgagt gggggtgtag tgggtgttcc 5821 tagctgccac gcctttgcct tcacctatgg gatcgtggct gtcagccttg agggtcagcc 5881 tggcccaggc tcccataggc ttaggagagg ccgcaattcc tacctgttca tccagacaga 5941 gggggacctg gaatcaaagt caagttgggg tagggggtcc atggggccat atctggcctg 6001 cagacagctc tggttagcta tgggctgagg tctggattct gccttgtgac tggagactgg 6061 gcgccatccc gtggcctctg agggcccagt ttgttcgtga cccatgctgc agagggagat 6121 acccaggctc ctggacctca gggcctgcct ggcactgcag gccaggttct ctttttattt 6181 ctgagacggg gtcttgtgtt gcccaggctg gagtgtaatg gcacaaccat ggctcactgc 6241 agcctcaact ttgggctcaa gcaattctcc tgcctcagcc tcccaagtag ctgaaactac 6301 acaggcatgc cccagcacgc ccagctagtt gcaggtcaga ttctcattgt tctacagggc 6361 cctgagttaa atactctcgc aagaagaaac caagcctggc ctgccttccc tctgctagaa 6421 gctgtgattg acaccagcag agaatgaagg aagaaaaggg ggtgaggatc ccttgcaggg 6481 atgccgttta ccccaaacac cacctggtgc atagcagttg ttctggaaat gatccggtcc 6541 ccccaggagg cctggactct caactgtgca cagtggccta ctggcagaga ggaaggtggt 6601 acccttcctc ctgtgttatc ttggaggtcc cctgaagggc tctctggggt ggttctagct 6661 cttttggtct gatttctgca gtggtgagcc ctgggccacc ttgggccact taatcattca 6721 acccccattc attgagtgac cactctacgg tgggggaggc tactgagatg acctggacaa 6781 ggaccctgcc ctggaggagc tgtcagtctg gaagtgagga tttaattcat ttgcccattc 6841 attcattcat tcattcattc attgaggact taattcattt gctcattcat tcattcattt 6901 gctcattcat ccattcattc actcattcat ccattcattc atccatccat ccatccatcc 6961 atccaatcac tatttgtgcc agatagtgcg ggtatagagg agaaccaacc agatgtgttc 7021 cgtgtcctca ccaggcaccc agtttaatgg ggaagacatc acaagcacga aggcaaacaa 7081 atgagtgtac agtgacatgc tgtgatcata ggaagagaga gcagagactt tgatgaacac 7141 gagcatcggg tgatgttcat tatgtcgatt gtggtggtgg tcttgcaggt gtagacatac 7201 ttcaaacctt atctaattgg gcctgctgtg gtgacgcatg cttgtaatcc cagcattttg 7261 ggaagctgag gtgggaggat cacttgagcc caggagctca aggctgcagt gagctatgat 7321 tgcaccactg cactccagcc tgggtgacag aacaagaacc tgactcttaa aaattaaaat 7381 aggccaggca ggcgtggtg //